公开(公告)号：US11076786B2

公开(公告)日：2021-08-03

申请号：US16589437

申请日：2019-10-01

申请人： Sohini Roy Choudhury ,  Yogeswaran Umasankar ,  Shekhar Bhansali ,  Robert S. Kirsner ,  Hadar A. Lev-Tov

发明人： Sohini Roy Choudhury ,  Yogeswaran Umasankar ,  Shekhar Bhansali ,  Robert S. Kirsner ,  Hadar A. Lev-Tov

IPC分类号： A61B5/1486 ,  A61B5/20 ,  A61B5/145 ,  A61B5/00

摘要： The subject invention provides sensor systems that can detect biomarkers related to wound healing (e.g., uric acid, adenosine, arginine and/or xanthine). In one embodiment, the subject invention pertains to materials and methods for monitoring biomarkers non-invasively in a wound and a biofluid (e.g., sweat) in the proximity of the wound, optionally, including other physiological fluids. Skin based, non-invasive enzymatic electrochemical biosensor on a wearable platform (e.g., sweat patch) that can evaluate the healing of wounds through assessment of its biomarker levels are provided. This non-invasive detection from physiologically biofluids can reduce or eliminate occlusion effects.