公开(公告)号：US20070111209A1

公开(公告)日：2007-05-17

申请号：US10571865

申请日：2004-09-17

申请人： Soley Bjornsdottir ,  Augustine Kong ,  Thorgeir Thorgeirsson

发明人： Soley Bjornsdottir ,  Augustine Kong ,  Thorgeir Thorgeirsson

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/172

摘要： An association between psychiatric disorders and disorders comorbid with psychiatric disorders, and genetic markers in the 8p23 genomic region is described. Markers are also provided to diagnose or detect a susceptibility to disorders comorbid with panic disorder and independently of comorbidity with panic disorder. Methods and surrogate markers for detecting the orientation of the Inv8p23 inversion fragment, thereby diagnosing psychiatric disorders or comorbid disorders or a susceptibility to psychiatric disorders or comorbid disorders, are also disclosed. The methods described herein are also useful for determining responsiveness of drugs useful for treating psychiatric disorders.

摘要翻译： 描述了精神障碍和与精神疾病共存的疾病之间的关联，以及8p23基因组区域中的遗传标记。 还提供标记物以诊断或检测与恐慌症并发症并发症和惊恐障碍并发症的易感性。 还公开了用于检测Inv8p23反转片段取向的方法和替代标记，从而诊断精神疾病或并发症，或对精神病或合并病症的易感性。 本文描述的方法也可用于确定用于治疗精神疾病的药物的反应性。