公开(公告)号：US20110304259A1

公开(公告)日：2011-12-15

申请号：US12815960

申请日：2010-06-15

Applicant: Richard Speer ,  Stuart Denham ,  Henry Hall ,  Brian Jones

Inventor： Richard Speer ,  Stuart Denham ,  Henry Hall ,  Brian Jones

IPC: H01J61/36 ,  H01J1/88

CPC classification number: H01J61/0672

Abstract: A mount (30) for a fluorescent lamp (32) has a glass flare (34) with a first portion (36) penetrating the fluorescent lamp (32) and a second portion (38) the fluorescent lamp (32). Two spaced-apart lead-in wires (40, 42) are sealed in the glass flare (34): and an electron emitter (12) is fixed between the spaced-apart lead-in wires (40, 42) and mated thereto by an electrical connection (46). The electron emitter (12) comprises a substrate (10) of a first material having an electron emitting material (11) thereon and two ends (20,22) and an element (23) mechanically and electrically fixed to each of the ends (20, 22), the element (23) comprising a second material different from the first material and is used to make the electrical connection (46) between the ends (20, 22) and the lead-in wires (40, 42).

Abstract translation: 用于荧光灯（32）的安装座（30）具有玻璃光阑（34），其中穿过荧光灯（32）的第一部分（36）和荧光灯（32）的第二部分（38）。 两个间隔开的引入线（40,42）被密封在玻璃光阑（34）中，并且电子发射器（12）固定在间隔开的引入线（40,42）之间，并通过 电连接（46）。 电子发射器（12）包括其上具有电子发射材料（11）的第一材料的基底（10）和两端（20,22）以及机械和电气固定到每个端部（20）的元件（23） ，22），所述元件（23）包括与所述第一材料不同的第二材料，并且用于在所述端部（20,22）和所述引入线（40,42）之间形成所述电连接（46）。

公开(公告)号：US09345705B2

公开(公告)日：2016-05-24

申请号：US14344190

申请日：2012-09-11

Applicant: Stuart Denham Shumway ,  Carlo Toniatti ,  Brian Scott Roberts ,  Melissa M. Martin

Inventor： Stuart Denham Shumway ,  Carlo Toniatti ,  Brian Scott Roberts ,  Melissa M. Martin

IPC: A61K31/519 ,  C07D487/02 ,  A61K31/506 ,  A61K45/06

CPC classification number: A61K31/519 ,  A61K31/506 ,  A61K45/06 ,  A61K2300/00

Abstract: The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell lung cancer and ovarian cancer, by administering a combination of a WEE1 inhibitor and a CHK1 inhibitor, wherein the WEE1 inhibitor is MK-1775 or a pharmaceutically acceptable salt thereof, or MK-3652 or a pharmaceutically acceptable salt thereof, and the CHK1 inhibitor is MK-8776 or a pharmaceutically acceptable salt thereof, or SCH900444 or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明提供了通过施用WEE1抑制剂和CHK1抑制剂的组合来治疗选自乳腺癌，黑素瘤，结肠直肠癌，非小细胞肺癌和卵巢癌的癌症的方法，其中 WEE1抑制剂是MK-1775或其药学上可接受的盐或MK-3652或其药学上可接受的盐，CHK1抑制剂是MK-8776或其药学上可接受的盐或SCH900444或其药学上可接受的盐。

公开(公告)号：US20140343071A1

公开(公告)日：2014-11-20

申请号：US14344190

申请日：2012-09-11

Applicant: Stuart Denham Shumway ,  Carlo Toniatti ,  Brian Scott Roberts ,  Melissa M. Martin

Inventor： Stuart Denham Shumway ,  Carlo Toniatti ,  Brian Scott Roberts ,  Melissa M. Martin

IPC: A61K31/519 ,  A61K45/06

CPC classification number: A61K31/519 ,  A61K31/506 ,  A61K45/06 ,  A61K2300/00

Abstract: The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell lung cancer and ovarian cancer, by administering a combination of a WEE1 inhibitor and a CHK1 inhibitor, wherein the WEE1 inhibitor is MK-1775 or a pharmaceutically acceptable salt thereof, or MK-3652 or a pharmaceutically acceptable salt thereof, and the CHK1 inhibitor is MK-8776 or a pharmaceutically acceptable salt thereof, or SCH900444 or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明提供了通过施用WEE1抑制剂和CHK1抑制剂的组合来治疗选自乳腺癌，黑素瘤，结肠直肠癌，非小细胞肺癌和卵巢癌的癌症的方法，其中 WEE1抑制剂是MK-1775或其药学上可接受的盐或MK-3652或其药学上可接受的盐，CHK1抑制剂是MK-8776或其药学上可接受的盐或SCH900444或其药学上可接受的盐。

公开(公告)号：US08183760B2

公开(公告)日：2012-05-22

申请号：US12815960

申请日：2010-06-15

Applicant: Richard Speer ,  Stuart Denham ,  Henry Hall ,  Brian Jones

Inventor： Richard Speer ,  Stuart Denham ,  Henry Hall ,  Brian Jones

IPC: H01J63/04

CPC classification number: H01J61/0672

Abstract: A mount (30) for a fluorescent lamp (32) has a glass flare (34) with a first portion (36) penetrating the fluorescent lamp (32) and a second portion (38) the fluorescent lamp (32). Two spaced-apart lead-in wires (40, 42) are sealed in the glass flare (34): and an electron emitter (12) is fixed between the spaced-apart lead-in wires (40, 42) and mated thereto by an electrical connection (46). The electron emitter (12) comprises a substrate (10) of a first material having an electron emitting material (11) thereon and two ends (20,22) and an element (23) mechanically and electrically fixed to each of the ends (20, 22), the element (23) comprising a second material different from the first material and is used to make the electrical connection (46) between the ends (20, 22) and the lead-in wires (40, 42).

Abstract translation: 用于荧光灯（32）的安装座（30）具有玻璃光阑（34），其中穿过荧光灯（32）的第一部分（36）和荧光灯（32）的第二部分（38）。 两个间隔开的引入线（40,42）被密封在玻璃光阑（34）中，并且电子发射器（12）固定在间隔开的引入线（40,42）之间，并通过 电连接（46）。 电子发射器（12）包括其上具有电子发射材料（11）的第一材料的基底（10）和两端（20,22）以及机械和电气固定到每个端部（20）的元件（23） ，22），所述元件（23）包括与所述第一材料不同的第二材料，并且用于在所述端部（20,22）和所述引入线（40,42）之间形成所述电连接（46）。