CONTINUOUS THROUGHPUT LYOPHILIZER-POWDER FILLER WITHIN A STERILE BOUNDARY

    公开(公告)号:US20230324118A1

    公开(公告)日:2023-10-12

    申请号:US18037246

    申请日:2021-11-16

    摘要: A continuous feed lyophilizer drying chamber that has an overall internal volume, a primly drying stage portion having a primary drying stage internal volume, a secondary drying stage portion having an internal volume, a frozen formulation feed inlet that provides frozen formulation droplets into the internal volume of the primary drying stage of the drying chamber and a dried particle outlet proximate an end of the continuous feed lyophilizer drying chamber configured to provide dried formulation droplet particles. The primary drying stage typically makes up from about 65-75% of the overall internal volume of the drying chamber and the secondary drying stage makes up from 25 to 35% of the overall internal volume of the drying chamber. The drying chamber dries frozen formulation droplets received into the primary drying stage internal volume via the frozen formulation feed inlet.

    CONTINUOUS THROUGHPUT LYOPHILIZER-POWDER FILLER WITHIN A STERILE BOUNDARY

    公开(公告)号:US20240151465A1

    公开(公告)日:2024-05-09

    申请号:US18412726

    申请日:2024-01-15

    摘要: A continuous feed lyophilizer drying chamber that has an overall internal volume, a primary drying stage portion having a primary drying stage internal volume, a secondary drying stage portion having an internal volume, a frozen formulation feed inlet that provides frozen formulation droplets into the internal volume of the primary drying stage of the drying chamber and a dried particle outlet proximate an end of the continuous feed lyophilizer drying chamber configured to provide dried formulation droplet particles. The primary drying stage typically makes up from about 65-75% of the overall internal volume of the drying chamber and the secondary drying stage makes up from 25 to 35% of the overall internal volume of the drying chamber. The drying chamber dries frozen formulation droplets received into the primary drying stage internal volume via the frozen formulation feed inlet.

    Continuous throughput lyophilizer-powder filler within a sterile boundary

    公开(公告)号:US11874060B2

    公开(公告)日:2024-01-16

    申请号:US18037246

    申请日:2021-11-16

    摘要: A continuous feed lyophilizer drying chamber that has an overall internal volume, a primly drying stage portion having a primary drying stage internal volume, a secondary drying stage portion having an internal volume, a frozen formulation feed inlet that provides frozen formulation droplets into the internal volume of the primary drying stage of the drying chamber and a dried particle outlet proximate an end of the continuous feed lyophilizer drying chamber configured to provide dried formulation droplet particles. The primary drying stage typically makes up from about 65-75% of the overall internal volume of the drying chamber and the secondary drying stage makes up from 25 to 35% of the overall internal volume of the drying chamber. The drying chamber dries frozen formulation droplets received into the primary drying stage internal volume via the frozen formulation feed inlet.