公开(公告)号：US08455014B2

公开(公告)日：2013-06-04

申请号：US12524122

申请日：2007-12-20

申请人： Jeong Min Lee ,  Chul Gyu Ha ,  Mu Hong Lee ,  Seung Ha Lee ,  Jae Yoon Leem ,  Wahn Soo Choi ,  Sung Hoon Jun ,  Jee Hun Park

发明人： Jeong Min Lee ,  Chul Gyu Ha ,  Mu Hong Lee ,  Seung Ha Lee ,  Jae Yoon Leem ,  Wahn Soo Choi ,  Sung Hoon Jun ,  Jee Hun Park

IPC分类号： A61K36/00

CPC分类号： A61K36/185 ,  A61K36/24 ,  A61K2300/00

摘要： The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory diseases comprising a mixture of herbal extracts of Trachelospermi caulis and Pyrola japonica as active ingredients. More particularly, the pharmaceutical composition of the present invention comprises a mixture of herbal extracts of Trachelospermi caulis and Pyrola japonica in a predetermined range thereby exhibiting superior on therapeutic effects for the treatment of pains, acute inflammation, secretion of enzymes associated with factors inducing inflammation, and production of NO, iNOS, etc., as compared to those prepared from single herbal drugs, thus being useful in the prevention and treatment of inflammatory diseases such as arthritis.

摘要翻译： 本发明涉及一种用于预防和治疗炎性疾病的药物组合物，其包含作为活性成分的of of草药提取物和茯苓的混合物。 更具体地说，本发明的药物组合物包含预定范围内的气管切片和Py炙草药提取物的混合物，从而对治疗疼痛，急性炎症，与引起炎症的因子分泌相关的酶的分泌具有优异的治疗效果， 和NO，iNOS等的生产，与单一草药相比，可用于预防和治疗关节炎等炎性疾病。

公开(公告)号：US20090317495A1

公开(公告)日：2009-12-24

申请号：US12524122

申请日：2007-12-20

申请人： Jeong Min Lee ,  Chul Gyu Ha ,  Mu Hong Lee ,  Seung Ha Lee ,  Jae Yoon Leem ,  Wahn Soo Choi ,  Sung Hoon Jun ,  Jee Hun Park

发明人： Jeong Min Lee ,  Chul Gyu Ha ,  Mu Hong Lee ,  Seung Ha Lee ,  Jae Yoon Leem ,  Wahn Soo Choi ,  Sung Hoon Jun ,  Jee Hun Park

IPC分类号： A61K36/24 ,  A61P29/00

CPC分类号： A61K36/185 ,  A61K36/24 ,  A61K2300/00

摘要： The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory diseases comprising a mixture of herbal extracts of Trachelospermi caulis and Pyrola japonica as active ingredients. More particularly, the pharmaceutical composition of the present invention comprises a mixture of herbal extracts of Trachelospermi caulis and Pyrola japonica in a predetermined range thereby exhibiting superior on therapeutic effects for the treatment of pains, acute inflammation, secretion of enzymes associated with factors inducing inflammation, and production of NO, iNOS, etc., as compared to those prepared from single herbal drugs, thus being useful in the prevention and treatment of inflammatory diseases such as arthritis.

摘要翻译： 本发明涉及一种用于预防和治疗炎性疾病的药物组合物，其包含作为活性成分的of of草药提取物和茯苓的混合物。 更具体地说，本发明的药物组合物包含预定范围内的气管切片和Py炙草药提取物的混合物，从而对治疗疼痛，急性炎症，与引起炎症的因子分泌相关的酶的分泌具有优异的治疗效果， 和NO，iNOS等的生产，与单一草药相比，可用于预防和治疗关节炎等炎性疾病。

公开(公告)号：US20090285913A1

公开(公告)日：2009-11-19

申请号：US12307091

申请日：2007-07-03

申请人： Jeong Min Lee ,  Chul Gyu Ha ,  Mu Hong Lee ,  Seung Ha Lee ,  Jae Yoon Leem ,  Sung Hoon Jun ,  Wahn Soo Choi ,  Jee Hun Park

发明人： Jeong Min Lee ,  Chul Gyu Ha ,  Mu Hong Lee ,  Seung Ha Lee ,  Jae Yoon Leem ,  Sung Hoon Jun ,  Wahn Soo Choi ,  Jee Hun Park

IPC分类号： A61K36/24 ,  A61P29/00

CPC分类号： A61K36/24 ,  A61K2236/333 ,  A61K2236/51

摘要： The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory diseases comprising The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory diseases comprising Trachelospermi caulis extract as an active ingredient. More particularly, the pharmaceutical composition of the present invention is characterized in that it is standardized and formulated so that the arctiin is contained in the Trachelospermi caulis extract within a predetermined range to exhibit excellent inhibitory effects on pains, acute inflammation, acute edema, production of iNOS, and TNF-Yá, activation of the enzymes of MAP kinases and NFYêB, thus effective in the prevention and treatment of inflammatory diseases such as arthritis.

摘要翻译： 本发明涉及用于预防和治疗炎症性疾病的药物组合物，其包含本发明涉及用于预防和治疗包括拔丝菌提取物作为活性成分的炎性疾病的药物组合物。 更具体地说，本发明的药物组合物的特征在于其标准化和配制，使得在预定范围内含有三氯乙酸提取物中的arctiin显示出优异的对疼痛，急性炎症，急性水肿，急性水肿的产生 iNOS和TNF-Ya，MAP激酶和NFYêB的酶的活化，因此有效预防和治疗炎性疾病如关节炎。