公开(公告)号：US08093384B2

公开(公告)日：2012-01-10

申请号：US12086994

申请日：2006-12-14

Applicant: Pankaj Kumar Nathani ,  Sunil Dnyaneshwar Narode ,  Mohammad Jaweed Mukarram Siddiqui

Inventor： Pankaj Kumar Nathani ,  Sunil Dnyaneshwar Narode ,  Mohammad Jaweed Mukarram Siddiqui

IPC: C07D239/72

CPC classification number: C07D405/12 ,  C07D239/84

Abstract: The invention relates to processes for the preparation of alfuzosin or pharmaceutically acceptable salts thereof in high purity. More particularly, it relates to the preparation of pure crystalline alfuzosin base. The invention also relates to pharmaceutical compositions that include the pure alfuzosin or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明涉及高纯度制备阿夫唑嗪或其药学上可接受的盐的方法。 更具体地说，涉及纯结晶阿夫唑嗪碱的制备。 本发明还涉及包含纯阿夫唑嗪或其药学上可接受的盐的药物组合物。

公开(公告)号：US20090312351A1

公开(公告)日：2009-12-17

申请号：US12086994

申请日：2006-12-14

Applicant: Pankaj Kumar Nathani ,  Sunil Dnyaneshwar Narode ,  Mohammed Jaweed Mukarram Siddiqui

Inventor： Pankaj Kumar Nathani ,  Sunil Dnyaneshwar Narode ,  Mohammed Jaweed Mukarram Siddiqui

IPC: A61K31/517 ,  C07D239/95 ,  A61P19/00

CPC classification number: C07D405/12 ,  C07D239/84

Abstract: The invention relates to processes for the preparation of alfuzosin or pharmaceutically acceptable salts thereof in high purity. More particularly, it relates to the preparation of pure crystalline alfuzosin base. The invention also relates to pharmaceutical compositions that include the pure alfuzosin or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明涉及高纯度制备阿夫唑嗪或其药学上可接受的盐的方法。 更具体地说，涉及纯结晶阿夫唑嗪碱的制备。 本发明还涉及包含纯阿夫唑嗪或其药学上可接受的盐的药物组合物。