公开(公告)号：US09249225B2

公开(公告)日：2016-02-02

申请号：US13699944

申请日：2010-12-10

Applicant: John R. Ohlfest ,  Karen Himmel Ohlfest ,  Jayanth Panyam ,  Suresh Kumar Swaminathan ,  Daniel A. Vallera

Inventor： John R. Ohlfest ,  Jayanth Panyam ,  Suresh Kumar Swaminathan ,  Daniel A. Vallera

IPC: C07K16/28 ,  A61K39/00

CPC classification number: C07K16/22 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/2863 ,  C07K16/2896 ,  C07K16/30 ,  C07K16/3015 ,  C07K16/303 ,  C07K16/3046 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2319/21 ,  C07K2319/42 ,  C07K2319/55 ,  G01N2333/70596

Abstract: Disclosed herein are a monoclonal antibody that specifically binds to human CD 133 and single-chain variable fragments thereof. Also disclosed herein is a hybridoma that produces the monoclonal antibody that specifically binds to human CD133.

Abstract translation: 本文公开了特异性结合人CD133及其单链可变片段的单克隆抗体。 本文还公开了产生特异性结合人CD133的单克隆抗体的杂交瘤。