公开(公告)号：US20230355307A1

公开(公告)日：2023-11-09

申请号：US18026134

申请日：2021-08-20

申请人： THE FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIVERSITY

发明人： Zhihu Zou ,  Song Fan ,  Li Zhang ,  Aiping Wang ,  Meng Zhang ,  Shuiping Yin ,  Changsheng Zhan ,  Yongtao Hu ,  Zongyao Hao ,  Chaozhao Liang

IPC分类号： A61B18/24

CPC分类号： A61B18/24 ,  A61B2018/00601

摘要： A laser resectoscope for minor caliber includes a water back system, a water inlet system, a laser sheath system, an observation system. The water back system includes a water return pipe and a water outlet structure. The water inlet system includes a water inlet pipe and a water inlet structure. The laser sheath system includes a laser sheath, an optical fiber and a laser head. The observation system includes a mirror tube and an eyepiece. It is increased for the water return of the laser resectoscope, and the laser resectoscope in F24 can be used to meet the surgical requirements of the conventional laser resectoscope in F26 clinically.

公开(公告)号：US20230139076A1

公开(公告)日：2023-05-04

申请号：US17541457

申请日：2021-12-03

申请人： The First Affiliated Hospital of Anhui Medical University Ltd.

发明人： Yunxia Cao ,  Dongmei Ji ,  Yinan Du ,  Ning Zhang ,  Zhikang Zhang ,  Zhuoli Liu ,  Weiwei Zou ,  Kai Zong

IPC分类号： G16B50/30 ,  G06F17/18 ,  G16H50/30

摘要： A method for predicting mtDNA mutation threshold, fertility risk and oocyte retrieval number includes: establishing an incidence probability prediction model of mitochondrial mutation and estimating a mutation threshold s; establishing a fertility risk prediction model and predicting a fertility risk of a mutation carrier; and establishing an oocyte retrieval prediction model by binomial distribution and calculating oocyte retrieval number by PGT of a mutation carrier. The incidence probability prediction model is used to estimate a threshold value of common mtDNA mutations and predict a mother's fertility risk and the oocyte retrieval number by PGT. On the basis of the fertility risk prediction model and oocyte retrieval prediction model, the fertility risk and a minimum oocyte retrieval number by PGT needed to give birth to a healthy offspring can be calculated by knowing a mitochondrial DNA mutation ratio of mutation carrier which is helpful for genetic management and genetic consultation.