公开(公告)号：US20140288121A1

公开(公告)日：2014-09-25

申请号：US14214286

申请日：2014-03-14

Applicant: THE UNIVERSITY OF BRIGHTON ,  THE UNIVERSITY OF SUSSEX

Inventor： Somnath Mukhopadhyay ,  Jason Cunningham

IPC: C12Q1/68 ,  A61K31/4545

CPC classification number: C12Q1/6827 ,  C12Q1/6883 ,  C12Q2600/156

Abstract: The invention provides methods of providing a prognosis of asthma severity in children and young adults. More specifically, the invention relates to novel single nucleotide polymorphisms (SNPs), and the cumulative genetic association of these and other SNPs in various genes, with the prognosis of asthma severity. The invention also extends to kits and other prognostic tools used to provide the prognosis of asthma severity.

Abstract translation: 本发明提供了在儿童和青少年中提供哮喘严重程度的预后的方法。 更具体地，本发明涉及新型单核苷酸多态性（SNP），以及这些和其他SNP在各种基因中的累积遗传关联，以及哮喘严重程度的预后。 本发明还扩展到用于提供哮喘严重程度的预后的试剂盒和其它预后工具。