公开(公告)号：US5175160A

公开(公告)日：1992-12-29

申请号：US747416

申请日：1991-08-19

申请人： Toshihiro Takahata ,  Masakazu Takei ,  Masahiro Kato ,  Tadayoshi Miura ,  Toshiyuki Yoshioka

发明人： Toshihiro Takahata ,  Masakazu Takei ,  Masahiro Kato ,  Tadayoshi Miura ,  Toshiyuki Yoshioka

IPC分类号： A61K31/535

CPC分类号： A61K31/535

摘要： An antimicrobial agent for animals is disclosed. The agent comprises as an effective component a racemate of a 3S-type compound of a pyrido[1,2,3-de][1,4]benzoxazine derivative represented by the formula (I): ##STR1## wherein R is a C.sub.1-6 alkyl group, provided that R cannot be a methyl group when the pyrido[1,2,3-de][1,4]benzoxazine derivative is a racemate, or a salt or a hydrate thereof. The compounds possess a low toxicity, are safe antimicrobial agents for animals, have a broader antimicrobial spectrum, and are effective against various infectious diseases of animals.

摘要翻译： 公开了一种用于动物的抗微生物剂。 作为有效成分，可以举出式（I）表示的吡啶并[1,2,3-de] [1,4]苯并恶嗪衍生物的3S型化合物的外消旋物：其中R 当吡啶并[1,2,3-de] [1,4]苯并恶嗪衍生物是外消旋物或其盐或其水合物时，R不能为甲基。 该化合物具有低毒性，是动物的安全抗微生物剂，具有更广泛的抗菌谱，对各种动物感染性疾病有效。