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公开(公告)号:US20130225569A1
公开(公告)日:2013-08-29
申请号:US13819166
申请日:2011-07-29
申请人: Lars Burgdorf , Melanie Schultz , Tatjana Ross , Brian Hodous , Justin Potnick , Amanda E. Sutton , Bayard R. Huck
发明人: Lars Burgdorf , Melanie Schultz , Tatjana Ross , Brian Hodous , Justin Potnick , Amanda E. Sutton , Bayard R. Huck
IPC分类号: C07D491/048 , A61K45/06 , A61K31/4355 , A61K31/496 , A61K31/5377 , A61K31/5383 , A61K31/506 , C07D519/00 , A61K31/4709
CPC分类号: C07D491/048 , A61K31/4355 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07D491/04 , C07D519/00
摘要: Compounds of the formula I in which R1 and R2 have the meanings indicated in Claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of rheumatoid arthritis and/or systemic lupus
摘要翻译: 其中R1和R2具有权利要求1所述含义的式I化合物是Syk的抑制剂,并且可以用于治疗类风湿性关节炎和/或系统性红斑狼疮
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公开(公告)号:US09006440B2
公开(公告)日:2015-04-14
申请号:US13819166
申请日:2011-07-29
申请人: Lars Burgdorf , Melanie Schultz , Tatjana Ross , Brian Hodous , Justin Potnick , Amanda E. Sutton , Bayard R. Huck
发明人: Lars Burgdorf , Melanie Schultz , Tatjana Ross , Brian Hodous , Justin Potnick , Amanda E. Sutton , Bayard R. Huck
IPC分类号: C07D491/048 , A61K31/4355 , C07D491/04 , C07D519/00 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06
CPC分类号: C07D491/048 , A61K31/4355 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07D491/04 , C07D519/00
摘要: Compounds of the formula I in which R1 and R2 have the meanings indicated in Claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of rheumatoid arthritis and/or systemic lupus.
摘要翻译: 其中R1和R2具有权利要求1所述含义的式I化合物是Syk的抑制剂,并且可以用于治疗类风湿性关节炎和/或系统性红斑狼疮。
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