公开(公告)号：US20110046015A1

公开(公告)日：2011-02-24

申请号：US12864619

申请日：2009-01-29

申请人： Hiroyuki Honda ,  Tsutomu Kawabe ,  Mina Okochi ,  Miyoko Matsushima ,  Naoki Matsumoto ,  Mitsuo Kawase ,  Yasuko Yoshida ,  Tomokazu Takase

发明人： Hiroyuki Honda ,  Tsutomu Kawabe ,  Mina Okochi ,  Miyoko Matsushima ,  Naoki Matsumoto ,  Mitsuo Kawase ,  Yasuko Yoshida ,  Tomokazu Takase

IPC分类号： C40B40/10 ,  C07K1/00 ,  C07K2/00 ,  C09K3/00

CPC分类号： G01N33/54393

摘要： Disclosed is a peptide immobilization technique which can achieve the immobilization of a satisfactory quantity of a peptide on a solid support. In the immobilization of a peptide on a solid support, a surfactant is allowed to coexist on the solid support together with the peptide. In this manner, the quantity of the peptide immobilized on the solid support can be increased.

摘要翻译： 公开了一种肽固定技术，其可以实现将令人满意的量的肽固定在固体支持物上。 在将肽固定在固体支持物上时，允许表面活性剂与肽一起共存在固体支持物上。 以这种方式，可以增加固定在固体支持物上的肽的量。

公开(公告)号：US20120215127A1

公开(公告)日：2012-08-23

申请号：US13502320

申请日：2010-08-10

申请人： Mitsuhiro Shikida ,  Tsutomu Kawabe ,  Miyoko Matsushima ,  Takuo Yokota ,  Satoshi Iwai ,  Naoyuki Matsunaga

发明人： Mitsuhiro Shikida ,  Tsutomu Kawabe ,  Miyoko Matsushima ,  Takuo Yokota ,  Satoshi Iwai ,  Naoyuki Matsunaga

IPC分类号： A61B5/103 ,  A61B5/087

CPC分类号： A61B5/028 ,  A61B5/0031 ,  A61B2503/40 ,  G01F1/6845 ,  G01F1/692

摘要： A flow sensor measures an amount of flow of a medium flowing inside a tubular organ of an organism by mounting a flexible substrate, upon which heaters are formed, inside a tube disposed in a manner so as to follow the tubular organ of the organism through which the medium is flowing, and by detecting a state of heat quantity generated from the heaters on the mounted flexible substrate being transmitted to the medium. In the flow sensor, at least the two heaters, formed upon the flexible substrate, respectively form symmetrical structures with identical heating capabilities under identical conditions, and the linear members, which supply power to the heaters from outside the organism, form symmetrical structures with identical heating capabilities under identical conditions, thereby allowing temperature distribution of the heaters and linear members inside the tube to he symmetrical. The plurality of linear members protrude in a manner so as to intersect from inside the tubular organ to outside the organism.

摘要翻译： 流量传感器通过将在其上形成有加热器的柔性基底安装在以与生物体的管状器官相关的方式设置的管中，将柔性基底安装在生物体的管状器官内部， 介质流动，并且通过检测从安装的柔性基板上的加热器产生的热量的状态被传送到介质。 在流量传感器中，形成在柔性基板上的至少两个加热器在相同条件下分别形成具有相同加热能力的对称结构，并且从生物体外部向加热器供电的线性部件形成具有相同的对称结构 在相同条件下的加热能力，从而允许管内的加热器和线性部件的温度分布使其对称。 多个线状构件以与管状器官内部相交的方式突出到生物体的外部。