公开(公告)号：US20140106976A1

公开(公告)日：2014-04-17

申请号：US13834260

申请日：2013-03-15

申请人： Karen Sachs ,  Mohammed N. AlQuraishi ,  Solomon Itani ,  Garry P. Nolan ,  Sean C. Bendall ,  Tyler J. Burns

发明人： Karen Sachs ,  Mohammed N. AlQuraishi ,  Solomon Itani ,  Garry P. Nolan ,  Sean C. Bendall ,  Tyler J. Burns

IPC分类号： G06F19/18

CPC分类号： G16B20/00

摘要： A method and apparatus for simultaneously determining multiple different biological molecule types in a sample include labeling each different biological molecule type in a biological sample with a unique combination of a plurality of labels. Each different biological molecule type is selected from a population of M different biological molecules types. The plurality of labels is selected from a population of L different labels; and, M is greater than L. Measurements are obtained of relative abundances of the L different labels in the sample. Relative abundance of up to M different biological molecule types in the sample are determined based on the measurements and a method of compressed sensing.

摘要翻译： 用于同时测定样品中多个不同生物分子类型的方法和装置包括用多个标记的独特组合标记生物样品中的每种不同生物分子类型。 每种不同的生物分子类型选自M种不同生物分子类型的群体。 多个标签选自L个不同标签的群体; 并且M大于L.测量样品中L个不同标签的相对丰度。 基于测量和压缩感测的方法确定样品中多达M种不同生物分子类型的相对丰度。