-
公开(公告)号:US20120232325A1
公开(公告)日:2012-09-13
申请号:US13403915
申请日:2012-02-23
申请人: Joyce H. Keyak , Tadashi Kaneko , Harry B. Skinner , Varun Sehgal
发明人: Joyce H. Keyak , Tadashi Kaneko , Harry B. Skinner , Varun Sehgal
CPC分类号: A61L24/0015 , A61K51/1203 , A61K51/1279 , A61L2300/102 , A61L2300/44 , A61N5/1014
摘要: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
摘要翻译: 描述了用放射性同位素处理靶组织的方法。 一些方法包括确定目标组织和待定位在靶组织附近的基质材料的表面之间的距离,并且基于所确定的距离,确定要与基质材料混合以获得所需活性浓度的活性。 一些方法还包括将放射性同位素与基质材料混合。 在一些实施方案中,基质材料是骨粘固剂,并且靶组织是骨中的肿瘤。 放射性同位素可以是在水泥中混合形成放射性水泥的β-发射放射性同位素。
-
公开(公告)号:US09198989B2
公开(公告)日:2015-12-01
申请号:US13403915
申请日:2012-02-23
申请人: Joyce H. Keyak , Tadashi Kaneko , Harry B. Skinner , Varun Sehgal
发明人: Joyce H. Keyak , Tadashi Kaneko , Harry B. Skinner , Varun Sehgal
CPC分类号: A61L24/0015 , A61K51/1203 , A61K51/1279 , A61L2300/102 , A61L2300/44 , A61N5/1014
摘要: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
摘要翻译: 描述了用放射性同位素处理靶组织的方法。 一些方法包括确定目标组织和待定位在靶组织附近的基质材料的表面之间的距离,并且基于所确定的距离,确定要与基质材料混合以获得所需活性浓度的活性。 一些方法还包括将放射性同位素与基质材料混合。 在一些实施方案中,基质材料是骨粘固剂,并且靶组织是骨中的肿瘤。 放射性同位素可以是在水泥中混合形成放射性水泥的β-发射放射性同位素。
-