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公开(公告)号:US07192932B1
公开(公告)日:2007-03-20
申请号:US09428458
申请日:1999-10-28
申请人: Kjetil Taskén , Einar M. Aandahl , Pål Aukrust , Bjørn S. Skålhegg , Fredrik Müller , Stig Frøland , Vidar Hansson
发明人: Kjetil Taskén , Einar M. Aandahl , Pål Aukrust , Bjørn S. Skålhegg , Fredrik Müller , Stig Frøland , Vidar Hansson
IPC分类号: A61K31/70 , C07H19/00 , C07D273/00
CPC分类号: A61K31/70
摘要: Pharmaceutical compositions useful for treating immunosuppressive disease and containing compounds capable of inhibiting cAMP-dependent protein kinase A (PKA) as well as use of the same, are described.
摘要翻译: 描述了可用于治疗免疫抑制疾病和含有能够抑制cAMP依赖性蛋白激酶A(PKA)的化合物及其用途的药物组合物。
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公开(公告)号:US20050250727A1
公开(公告)日:2005-11-10
申请号:US11136560
申请日:2005-05-25
申请人: Kjetil Tasken , Einar Aandahl , Pal Aukrust , Bjorn Skalhegg , Fredrik Muller , Stig Froland , Vidar Hansson
发明人: Kjetil Tasken , Einar Aandahl , Pal Aukrust , Bjorn Skalhegg , Fredrik Muller , Stig Froland , Vidar Hansson
IPC分类号: A61K45/00 , A61K31/18 , A61K31/7076 , A61K31/7105 , A61K38/00 , A61K38/16 , A61K38/17 , A61P31/18 , A61P37/02 , A61P43/00 , C12N9/12 , C12N15/113 , A61K48/00
CPC分类号: C12N15/1137 , A61K38/005 , A61K38/1709 , C12N9/12 , C12N2310/121
摘要: Pharmaceutical compositions useful for treating immunosuppressive disease and containing compounds capable of inhibiting cAMP-dependent protein kinase A (PKA) as well as use of the same, are described.
摘要翻译: 描述了可用于治疗免疫抑制疾病和含有能够抑制cAMP依赖性蛋白激酶A(PKA)的化合物及其用途的药物组合物。
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3.
公开(公告)号:US07790738B2
公开(公告)日:2010-09-07
申请号:US10333657
申请日:2001-07-20
申请人: Kjetil Taskén , Michel Moutschen , Souad Rahmouni-Piette , Einar Martin Aandahl , Pål Aukrust , Stig S. Frøland , Christian C. Johansson , Vidar Hansson , Jo Klaveness
发明人: Kjetil Taskén , Michel Moutschen , Souad Rahmouni-Piette , Einar Martin Aandahl , Pål Aukrust , Stig S. Frøland , Christian C. Johansson , Vidar Hansson , Jo Klaveness
IPC分类号: A01N43/40 , A01N43/82 , A01N43/78 , A01N43/56 , A01N43/36 , A01N43/02 , A61K31/435 , A61K31/41 , A61K31/425 , A61K31/40 , A61K31/38 , A61K31/335
CPC分类号: A61K31/6615 , A61K31/18 , A61K31/365 , A61K31/381 , A61K31/405 , A61K31/407 , A61K31/415 , A61K31/5415 , A61K31/675
摘要: The present invention provides a method of treating or preventing a disorder typified by an immunodificiency (e.g. HIV), wherein the patient is administered a COX-2 inhibitor or derivative or pharmaceutically acceptable salt thereof, preferably diisopropylfluorophasphate. L-745337, rofecoxib, NS 398, SC 58125, etodolac, meloxicam, celecoxib or nimesulide, and compositions and products containing the same or use of the same in preparing medicaments and for treatment.
摘要翻译: 本发明提供了治疗或预防以免疫功能为代表的疾病(例如HIV)的方法,其中给予患者COX-2抑制剂或其衍生物或药学上可接受的盐,优选氟代二异丙酯。 L-745337,罗非昔布,NS 398,SC 58125,依托度酸,美洛昔康,塞来考昔或尼美舒利,以及含有该组合物和产品的制备药物和用于治疗的组合物和产品。
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