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公开(公告)号:US6071911A
公开(公告)日:2000-06-06
申请号:US370640
申请日:1999-08-06
申请人: Hans-Joachim Lankau , Klaus Unverferth , Thomas Arnold , Reni Bartsch , Abgelika Rostock , Vladimir Granik , Sofia Grizik
发明人: Hans-Joachim Lankau , Klaus Unverferth , Thomas Arnold , Reni Bartsch , Abgelika Rostock , Vladimir Granik , Sofia Grizik
IPC分类号: A61K31/4412 , A61K31/4418 , A61K31/4425 , A61P25/08 , C07B61/00 , C07D213/73 , C07D213/74 , A61K31/535
CPC分类号: C07D213/73 , C07D213/74
摘要: Antiepileptic compounds of the formula ##STR1## wherein X is hydrogen, a C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl, trifluoromethoxy or halogen residue, A is an amino, C.sub.1-4 alkylamino, C.sub.1-4 dialkylamino, morpholino, piperidino or pyrrolidino residue, and n is a cardinal number from 0 to 5, and process for preparing the foregoing compounds and for their use as anticonvulsives.
摘要翻译: A为氨基,C 1-4烷基氨基,C 1-4二烷基氨基,吗啉代,哌啶子基或吡咯烷子基的残基,其中X为氢,C 1-4烷基,C 1-4烷氧基,三氟甲基,三氟甲氧基或卤素残基的抗癫痫化合物, n为0〜5的基数,以及上述化合物的制备方法及其作为抗惊厥药的用途。