公开(公告)号：US20240074775A1

公开(公告)日：2024-03-07

申请号：US18261246

申请日：2021-10-06

Applicant: WOMEN'S AND CHILDREN'S LOCAL HEALTH NETWORK INC. ,  THE UNIVERSITY OF ADELAIDE

Inventor： Martin DONNELLEY ,  Alexandra MCCARRON ,  David PARSONS

IPC: A61B17/24 ,  A61K48/00

CPC classification number: A61B17/24 ,  A61K48/0075 ,  A61B2017/242

Abstract: The present disclosure relates to non-surgical methods for delivery of an agent to the respiratory system of a subject, methods of treatment using delivery of agents to the respiratory system, devices for delivery of agents to the respiratory system, and use of such devices to deliver agents to the respiratory system. In certain embodiments, the present disclosure provides a provide a non-surgical method of delivering an agent to the respiratory system of a subject. The method comprises in vivo perturbation of the airway surface in one or more parts of the respiratory system in the subject and exposing the perturbed surface of the airway to the agent, thereby delivering the agent to the respiratory system of the subject.