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1.发明授权公开(公告)号：US08067390B2
公开(公告)日：2011-11-29
申请号：US12527684
申请日：2008-02-29
CPC分类号： C12N15/1136 , A61K9/127 , A61K45/06 , C12N2310/14 , C12N2320/31
摘要： The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmaceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein.
摘要翻译： 本发明涉及分子生物学和药物递送领域。 在某些实施方案中，本发明提供了包含靶向白细胞介素和中性脂质的siRNA的组合物，以及用癌症治疗人受试者的方法，包括向受试者施用药学有效量的白细胞介素-8拮抗剂或组合物作为 在此阐述。
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2.发明申请公开(公告)号：US20100172962A1
公开(公告)日：2010-07-08
申请号：US12527684
申请日：2008-02-29
IPC分类号： A61K9/127 , A61K31/7105 , A61K31/711 , A61K38/16 , A61K38/02 , A61K39/395 , A61K31/713 , A61P37/06
CPC分类号： C12N15/1136 , A61K9/127 , A61K45/06 , C12N2310/14 , C12N2320/31
摘要： The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmaceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein.
摘要翻译： 本发明涉及分子生物学和药物递送领域。 在某些实施方案中，本发明提供了包含靶向白细胞介素和中性脂质的siRNA的组合物，以及用癌症治疗人受试者的方法，包括向受试者施用药学有效量的白细胞介素-8拮抗剂或组合物作为 在此阐述。
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