公开(公告)号：US08249717B2

公开(公告)日：2012-08-21

申请号：US11779764

申请日：2007-07-18

申请人： Marina V. Brockway ,  Paul A. Haefner ,  Anthony V. Caparso ,  Wondimeneh Tesfavesus

发明人： Marina V. Brockway ,  Paul A. Haefner ,  Anthony V. Caparso ,  Wondimeneh Tesfavesus

IPC分类号： A61N1/00

CPC分类号： A61N1/36114 ,  A61N1/36117

摘要： A method embodiment comprises generating a neural stimulation signal for a neural stimulation therapy. The signal is generated during a duty cycle of a stimulation period to provide the neural stimulation therapy with an intensity at a therapy level for a portion of the duty cycle. In various embodiments, a ramp up protocol is implemented to begin the duty cycle, a ramp down protocol is implemented to end the duty cycle, or both the ramp up protocol and the ramp down protocol are implemented. The ramp up protocol includes ramping up the intensity from a non-zero first subthreshold level for the neural stimulation therapy at the beginning of the duty cycle to the therapy level. The ramp down protocol includes ramping down the intensity from the therapy intensity level to a non-zero second subthreshold level for the neural stimulation therapy at the end of the duty cycle.

摘要翻译： 方法实施例包括产生用于神经刺激治疗的神经刺激信号。 在刺激期的占空比期间产生信号，以在占空比的一部分的治疗水平上提供具有强度的神经刺激治疗。 在各种实施例中，实现斜坡上升协议以开始占空比，实现斜降协议以结束占空比，或者实现升温协议和斜降协议两者。 加速协议包括在占空比开始时到神经刺激治疗的非零第一亚阈值水平上升到治疗水平。 斜坡协议包括在占空比结束时将神经刺激治疗的强度从治疗强度水平向下降至非零秒次阈值水平。