公开(公告)号：US08507203B2

公开(公告)日：2013-08-13

申请号：US13433553

申请日：2012-03-29

Applicant: X. Chris Le ,  Camille Hamula ,  Xing-Fang Li

Inventor： X. Chris Le ,  Camille Hamula ,  Xing-Fang Li

IPC: C12Q1/68 ,  C07H21/02 ,  C07H21/04 ,  G01N33/569 ,  G01N33/53

CPC classification number: C12Q1/689

Abstract: The invention is directed to aptamers, methods and kits comprising same for detecting Streptococcus pyogenes. The method of screening a subject for Streptococcus pyogenes involves obtaining a body sample from the subject; contacting the sample or a bacterial culture of the sample with an aptamer or a panel of aptamers specific to S. pyogenes; and detecting the presence or absence of S. pyogenes in the sample or the bacterial culture, wherein binding of the aptamer is indicative of the presence of S. pyogenes.

Abstract translation: 本发明涉及用于检测化脓性链球菌的适体，方法和试剂盒。 筛选化脓性链球菌受试者的方法涉及从受试者获得身体样品; 使样品或细菌培养物与拟南芥特异性的适体或一组适体接触; 并检测样品或细菌培养物中是否存在化脓性链球菌，其中适体的结合指示化脓性链球菌的存在。

公开(公告)号：US20120276547A1

公开(公告)日：2012-11-01

申请号：US13433553

申请日：2012-03-29

Applicant: X. Chris LE ,  Camille HAMULA ,  Xing-Fang LI

Inventor： X. Chris LE ,  Camille HAMULA ,  Xing-Fang LI

IPC: C12Q1/68 ,  C07H21/04 ,  G01N21/64

CPC classification number: C12Q1/689

Abstract: The invention is directed to aptamers, methods and kits comprising same for detecting Streptococcus pyogenes. The method of screening a subject for Streptococcus pyogenes involves obtaining a body sample from the subject; contacting the sample or a bacterial culture of the sample with an aptamer or a panel of aptamers specific to S. pyogenes; and detecting the presence or absence of S. pyogenes in the sample or the bacterial culture, wherein binding of the aptamer is indicative of the presence of S. pyogenes.

Abstract translation: 本发明涉及用于检测化脓性链球菌的适体，方法和试剂盒。 筛选化脓性链球菌受试者的方法涉及从受试者获得身体样品; 使样品或细菌培养物与拟南芥特异性的适体或一组适体接触; 并检测样品或细菌培养物中是否存在化脓性链球菌，其中适体的结合指示化脓性链球菌的存在。