公开(公告)号：US20070037747A1

公开(公告)日：2007-02-15

申请号：US11497075

申请日：2006-08-01

申请人： Xiaopeng Ma ,  Bing Wang ,  Shaoqi Xi

发明人： Xiaopeng Ma ,  Bing Wang ,  Shaoqi Xi

IPC分类号： A61K38/22 ,  C07K14/575

CPC分类号： C07K14/57563 ,  A61K38/00

摘要： The present invention relates to an Exendin 4 polypeptide fragment, which has hypoglycemic activity, and can be used for the treatment of type II diabetes mellitus. The polypeptide sequence described herein is HGEGTX1TSDLSKQX2EEEAVX3LFIEWLKNGX4PX5, where X1 represents Phe or Tyr, X2 represents Met, Ile or Leu, X3 represents Lys, X4 represents Gly or deletion, X5 represents Arg or deletion. Additionally, the present invention relates to a method for the Exendin 4 polypeptide fragment preparation.

摘要翻译： 本发明涉及具有降血糖活性的毒蜥外泌肽4多肽片段，可用于治疗II型糖尿病。 本文所述的多肽序列是HGEGTX1TSDLSKQX2EEEAVX3LFIEWLKNGX4X5X，其中X 1代表Phe或Tyr，X 2表示 Met，Ile或Leu，X 3代表Lys，X 4代表Gly或缺失，X 5代表Arg或缺失。 另外，本发明涉及用于毒蜥外泌肽4多肽片段制备的方法。

公开(公告)号：US20090317702A1

公开(公告)日：2009-12-24

申请号：US12376179

申请日：2007-09-27

申请人： Long He ,  Jianhua Tang ,  Xiaopeng Ma

发明人： Long He ,  Jianhua Tang ,  Xiaopeng Ma

IPC分类号： H01M2/18 ,  H01M4/58 ,  H01M2/02

CPC分类号： H01M10/0525 ,  H01M2/14 ,  H01M2/1686 ,  H01M2/18 ,  H01M10/0585

摘要： A stacked-type lithium ion battery, comprising a core, a battery shell, and a cover plate; said core is placed in the battery shell, said cover plate is coupled to the battery shell in a sealed manner; said core comprises a plurality of layers of positive plates, negative plates, and membranes that are stacked together with each other, and the membrane is between the positive plate and the negative plate; wherein at least two membranes are in a 5-175° included angle between their tensile directions. Since the tensile directions of the membranes are different, the overall tensile strengths of the battery in all tensile directions are essentially same; therefore, the phenomenon of short circuit in the battery resulted from membrane rupture in lower tensile strength directions can be prevented, and the battery safety performance is greatly enhanced.

摘要翻译： 一种叠层型锂离子电池，包括芯，电池壳和盖板; 所述芯体放置在电池壳体中，所述盖板以密封的方式联接到电池壳体; 所述芯包括彼此堆叠在一起的多个正极板，负极板和膜，并且膜位于正极板和负极板之间; 其中至少两个膜在它们的拉伸方向之间夹角5-175°。 由于膜的拉伸方向不同，电池在所有拉伸方向的整体拉伸强度基本相同; 因此，可以防止在较低拉伸强度方向上由于膜破裂导致的电池短路现象，并且电池安全性能大大提高。

公开(公告)号：US07608587B2

公开(公告)日：2009-10-27

申请号：US11497075

申请日：2006-08-01

申请人： Xiaopeng Ma ,  Bing Wang ,  Shaoqi Xi

发明人： Xiaopeng Ma ,  Bing Wang ,  Shaoqi Xi

IPC分类号： A61K38/12

CPC分类号： C07K14/57563 ,  A61K38/00

摘要： The present invention relates to an Exendin 4 polypeptide fragment, which has hypoglycemic activity, and can be used for the treatment of type II diabetes mellitus. The polypeptide sequence described herein is HGEGTX1TSDLSKQX2EEEAVX3LFIEWLKNGX4PX5, where X1 represents Phe or Tyr, X2 represents Met, Ile or Leu, X3 represents Lys, X4 represents Gly or deletion, X5 represents Arg or deletion. Additionally, the present invention relates to a method for the Exendin 4 polypeptide fragment preparation.

摘要翻译： 本发明涉及具有降血糖活性的毒蜥外泌肽4多肽片段，可用于治疗II型糖尿病。 本文所述的多肽序列是HGEGTX1TSDLSKQX2EEEAVX3LFIEWLKNGX4PX5，其中X1表示Phe或Tyr，X2表示Met，Ile或Leu，X3表示Lys，X4表示Gly或缺失，X5表示Arg或缺失。 另外，本发明涉及用于毒蜥外泌肽4多肽片段制备的方法。