-
公开(公告)号:US09580717B2
公开(公告)日:2017-02-28
申请号:US13516758
申请日:2010-12-17
申请人: Youming Zhang , Jun Fu , Xiaoying Bian , Adrian Francis Stewart , Rolf Müller
发明人: Youming Zhang , Jun Fu , Xiaoying Bian , Adrian Francis Stewart , Rolf Müller
IPC分类号: C12N15/74 , C07D245/02 , C07D417/06 , C07D493/04 , C12N9/90 , C12N15/52 , C12P17/10 , C12P17/18 , C12N15/70 , A61K35/00 , C12N9/00
CPC分类号: C12N15/70 , A61K35/74 , A61K2035/11 , C07D245/02 , C07D417/06 , C07D493/04 , C07D498/22 , C07G17/00 , C07K5/06139 , C07K7/64 , C12N9/1288 , C12N9/90 , C12N9/93 , C12N15/52 , C12N15/74 , C12P17/10 , C12P17/181 , C12Y207/08007 , Y02P20/52
摘要: This invention is related to bacterial engineering and the heterologous expression of useful compounds. In particular, the invention relates to a heterologous host that has been engineered for expression of a gene which is capable of polyketide or non-ribosomal peptide synthesis. Methods of treating cancer are also disclosed.
摘要翻译: 本发明涉及细菌工程和有用化合物的异源表达。 特别地,本发明涉及已被改造用于表达能够进行聚酮化合物或非核糖体肽合成的基因的异源宿主。 还公开了治疗癌症的方法。
-
公开(公告)号:US20130089522A1
公开(公告)日:2013-04-11
申请号:US13516758
申请日:2010-12-17
申请人: Youming Zhang , Jun Fu , Xiaoying Bian , Francis Stewart , Rolf Muller
发明人: Youming Zhang , Jun Fu , Xiaoying Bian , Francis Stewart , Rolf Muller
CPC分类号: C12N15/70 , A61K35/74 , A61K2035/11 , C07D245/02 , C07D417/06 , C07D493/04 , C07D498/22 , C07G17/00 , C07K5/06139 , C07K7/64 , C12N9/1288 , C12N9/90 , C12N9/93 , C12N15/52 , C12N15/74 , C12P17/10 , C12P17/181 , C12Y207/08007 , Y02P20/52
摘要: This invention is related to bacterial engineering and the heterologous expression of useful compounds. In particular, the invention relates to a heterologous host that has been engineered for expression of a gene which is capable of polyketide or non-ribosomal peptide synthesis. Methods of treating cancer are also disclosed.
摘要翻译: 本发明涉及细菌工程和有用化合物的异源表达。 特别地,本发明涉及已被改造用于表达能够进行聚酮化合物或非核糖体肽合成的基因的异源宿主。 还公开了治疗癌症的方法。
-