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    Drop pill for treating coronary heart disease and preparation thereof
    1.
    发明申请
    Drop pill for treating coronary heart disease and preparation thereof 审中-公开
    用于治疗冠心病的药丸及其制备

    公开(公告)号：US20110195136A1

    公开(公告)日：2011-08-11

    申请号：US13122800

    申请日：2009-09-30

    申请人： Jianming Chen ,  Xijun Yan ,  Yonghong Zhu ,  Baoan Gao ,  Shunnan Zhang ,  Haiou Dong ,  Jizhong Zhang ,  Wei Li ,  Xinjiang Yan ,  Ying Zhao

    发明人： Jianming Chen ,  Xijun Yan ,  Yonghong Zhu ,  Baoan Gao ,  Shunnan Zhang ,  Haiou Dong ,  Jizhong Zhang ,  Wei Li ,  Xinjiang Yan ,  Ying Zhao

    IPC分类号： A61K36/254 ,  A61P9/00

    CPC分类号： A61K36/537 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/1694 ,  A61K31/045 ,  A61K36/258 ,  A61K2300/00

    摘要： The present invention relates to a drop pill for treating coronary heart disease, comprising an active pharmaceutical ingredient (API), a matrix adjuvant, a plastifying adjuvant, propylene glycol and water. the API is prepared from Radix salvia miltiorrhira, Panax notoginseng and Borneol; the matrix adjuvant is erythritol; the plastifying adjuvant is one or more selected from the group consisting of polyethylene glycols, xylitol, lactitol, mannitol, glycerine, soluble amylum, gelatin, methyl cellulose, sodium carboxymethycellulose (CMC-Na), hydroxypropyl methylcellulose (HPMC), arabic gum, alginic acid, dextrin, cyclodextrin (CD), citrate, glycerol acetate, dibutyl sebacate, refined coconut oil and castor oil; Wherein, relative to the total weight of the drop pill, the API is 1˜40 wt %, the plastifying adjuvant 0˜10 wt %, the propylene glycol 1˜10 wt %, the water 0˜10 wt % and the balance is the matrix adjuvant. The drop pills of the present invention are safe and non-toxic, low moisture absorption and rapid dissolution.

    摘要翻译： 本发明涉及用于治疗冠心病的滴丸，其包含活性药物成分（API），基质佐剂，塑化佐剂，丙二醇和水。 API是由丹参，三七和冰片制成的; 基质佐剂是赤藓醇; 增塑佐剂是选自聚乙二醇，木糖醇，乳糖醇，甘露醇，甘油，可溶性淀粉，明胶，甲基纤维素，羧甲基纤维素钠（CMC-Na），羟丙基甲基纤维素（HPMC），阿拉伯树胶，海藻酸 酸，糊精，环糊精（CD），柠檬酸盐，乙酸甘油酯，癸二酸二丁酯，精制椰子油和蓖麻油; 其中相对于滴丸的总重量，API为1〜40重量％，增塑助剂0〜10重量％，丙二醇1〜10重量％，水0〜10重量％，余量为 基质佐剂。 本发明的滴丸是安全无毒，低吸湿性和快速溶解的。

    PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF HYPERLIPIDEMIA, PROCESSES FOR PRODUCING THE SAME AND THE USE THEREOF
    3.
    发明申请
    PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF HYPERLIPIDEMIA, PROCESSES FOR PRODUCING THE SAME AND THE USE THEREOF 有权
    用于治疗和/或预防高脂药物的药物组合物，其生产方法及其用途

    公开(公告)号：US20090291154A1

    公开(公告)日：2009-11-26

    申请号：US11721245

    申请日：2005-12-05

    申请人： Xijun Yan ,  Boli Zhang ,  Zhixin Guo ,  Guoguang Zhu ,  Zhengliang Ye ,  Feng Wei ,  Ruizhi Luo

    发明人： Xijun Yan ,  Boli Zhang ,  Zhixin Guo ,  Guoguang Zhu ,  Zhengliang Ye ,  Feng Wei ,  Ruizhi Luo

    IPC分类号： A61K36/18 ,  A61P1/16 ,  A61P9/10

    CPC分类号： A61K36/704 ,  A61K36/258 ,  A61K36/537 ,  A61K36/734 ,  A61K2300/00

    摘要： The present invention discloses a pharmaceutical composition comprising Polygonum multiflorum Thunb, which comprises Polygonum multiflorum Thunb, Fructus Crataegi, Salvia miltiorrhiza Bunge and Radix Notoginseng. If needed, the pharmaceutical composition may comprise the pharmaceutically acceptable carriers. The weight ratio of Polygonum multiflorum Thunb, Salvia miltiorrhiza Bunge, Fructus Crataegi and Radix Notoginseng in the present composition is as follows: 10 to 20 parts of Polygonum multiflorum Thunb, 5 to 15 parts of Salvia miltiorrhiza Bunge, 10 to 20 parts of Fructus Crataegi and 1 to 10 parts of Radix Notoginseng. Also, the present invention discloses the methods for preparing the composition, including directly pulverizing the medicines into powder to produce the composition or preparing the medicines into the extracts and then make the extracts into drugs. The composition of the present invention has an effect of lowering blood lipid, and therefore can be used in preparation of drugs for treatment and/or prevention of hyperlipidemia. The present invention also discloses a method to treat and/or prevent hyperlipidemia.

    摘要翻译： 本发明公开了一种含有枸杞的药用组合物，其中包括茯苓，山楂，丹参和三七。 如果需要，药物组合物可以包含药学上可接受的载体。 本发明组合物中枸杞，丹参，三七的重量比如下：10〜20份枸杞，5〜15份丹参，10〜20份山楂 和三至三七。 此外，本发明公开了制备组合物的方法，包括将药物直接粉碎成粉末以制备组合物或将药物制备成提取物，然后将提取物制成药物。 本发明的组合物具有降低血脂的作用，因此可用于制备用于治疗和/或预防高脂血症的药物。 本发明还公开了治疗和/或预防高脂血症的方法。