公开(公告)号：US20240065992A1

公开(公告)日：2024-02-29

申请号：US18266070

申请日：2021-12-10

Applicant: KINKI UNIVERSITY ,  YASHIRO CO., LTD. ,  OSAKA UNIVERSITY

Inventor： Nobuhiro ZAIMA ,  Hirona KUGO ,  Motohiro KITANO ,  Yoshinori HIROTA ,  Ken-ichi HIRANO

IPC: A61K31/19 ,  A61P9/00

CPC classification number: A61K31/19 ,  A61P9/00

Abstract: An aortic aneurysm has few noticeable symptoms and is at high risk of rupture without a sign of abnormality. Further, if the aortic aneurysm ruptures, it causes a shock state due to massive blood loss and results in a very low survival rate. Thus, when the aortic aneurysm is found by physical examination or the like, surgery with a stent graft or the like needs to be performed according to the state of its progression.
A pharmaceutical composition for preventing and treating an aortic aneurysm including a medium chain fatty acid as a main component has an effect of inhibiting the occurrence and progression of the aortic aneurysm. Thus, when the aortic aneurysm is found, continuous intake of the composition can not only inhibit the progression of the aortic aneurysm but also mediate the regression of the aortic aneurysm, thereby producing the effect of improving vital prognosis.

公开(公告)号：US20220323385A1

公开(公告)日：2022-10-13

申请号：US17620406

申请日：2020-06-19

Applicant: KINKI UNIVERSITY ,  YASHIRO CO., LTD. ,  OSAKA UNIVERSITY

Inventor： Nobuhiro ZAIMA ,  Hirona KUGO ,  Motohiro KITANO ,  Yoshinori HIROTA ,  Ken-ichi HIRANO

IPC: A61K31/19 ,  A61P9/14 ,  A61K38/00

Abstract: An aortic aneurysm has few noticeable symptoms and is at high risk for rupture without a sign of abnormality. Further, if it ruptures, it causes a shock state due to massive blood loss and results in a very low survival rate. Thus, when the aortic aneurysm is found by physical examination or the like, a surgery with a stent graft or the like needs to be performed according to the state of its progression.
A pharmaceutical composition for preventing an aortic aneurysm including a medium chain fatty acid as a main component has an effect of inhibiting the occurrence and progression of the aortic aneurysm. Thus, when the aortic aneurysm is found, the composition through continuous intake can exhibit effects including inhibition of the progression of the aortic aneurysm and improvement in the vital prognosis.