Therapeutic Application Of Leonurine In Treating Cardiomyopathy
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    发明申请
    Therapeutic Application Of Leonurine In Treating Cardiomyopathy 审中-公开
    Leonurine治疗心肌病的治疗应用

    公开(公告)号:US20090036527A1

    公开(公告)日:2009-02-05

    申请号:US12185052

    申请日:2008-08-01

    IPC分类号: A61K31/221 C12N5/06 A61P9/10

    CPC分类号: A61K31/24

    摘要: The present invention provides methods for treating ischemic cardiomyopathy. In one embodiment, provided is a method of treating a disease characterized as ischemic cardiomyopathy, comprising administering to a subject suffering from said disease a pharmaceutical composition comprising therapeutically effective amount of synthesized Leonurine. The method induces at least one biochemical change to improve hypoxia myocardial cells survive rate, reduce LDH releasing from the ischemic myocardial cells, and reduce infarction area of cardiomyopathy in the subject.

    摘要翻译: 本发明提供治疗缺血性心肌病的方法。 在一个实施方案中,提供了治疗以缺血性心肌病为特征的疾病的方法,包括向患有所述疾病的受试者施用包含治疗有效量的合成的胆碱金属的药物组合物。 该方法诱导至少一种生物化学变化,以改善缺氧心肌细胞的存活率,减少缺血心肌细胞的LDH释放,并减少受试者心肌病的梗死面积。