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公开(公告)号:US20120238572A1
公开(公告)日:2012-09-20
申请号:US13487434
申请日:2012-06-04
申请人: Wei-Guo Su , Weihan Zhang , Xiaoqiang Yan , Yumin Cui , Yongxin Red , Jifeng Duan
发明人: Wei-Guo Su , Weihan Zhang , Xiaoqiang Yan , Yumin Cui , Yongxin Red , Jifeng Duan
IPC分类号: A61K31/517 , A61K31/5377 , A61P27/02 , A61K31/4709
CPC分类号: C07D405/12
摘要: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
摘要翻译: 下式定义的喹唑啉衍生物:其中R1,R2,R3,R4,R5,R6,R7,R8,R9,R10,X和Z如本文所定义。 它还公开了用这些化合物之一治疗血管生成相关病症的方法。