公开(公告)号：US20090176006A1

公开(公告)日：2009-07-09

申请号：US11379993

申请日：2006-04-24

申请人： Jason T. Flodin ,  Joseph D. Lichtenhan ,  Joseph J. Schwab ,  Yi-Zhong An ,  Xuan Fu ,  Zachary Kemp

发明人： Jason T. Flodin ,  Joseph D. Lichtenhan ,  Joseph J. Schwab ,  Yi-Zhong An ,  Xuan Fu ,  Zachary Kemp

IPC分类号： B05D3/00

CPC分类号： A61L27/18 ,  A61L2400/12 ,  C08L83/04

摘要： Nanostructured chemicals such as polyhedral oligomeric silsesquioxanes, polyhedral oligomeric silicates, and polyhedral oligomeric metallasesquioxanes are attached to living and nonliving systems as biomaterials to provide a nanoscopic topology that favors biomimetic function and cellular modulation. The resulting surface is nanoscopically thin, nanoscopically dispersed, provides systematic chemistry, surface area, surface volume, surface topology, and is essentially free of impurities, and has controllable properties through selection of composition, R groups, nanostructure size and topology. Highly shape specific and chemically tailorable nanostructured molecules are sized to biological material dimensions and are compatible with all sterilization methods.

摘要翻译： 纳米结构化学物质​​如多面体低聚倍半硅氧烷，多面体低聚硅酸盐和多面体低聚金属氧化物倍半硅氧烷作为生物材料连接到生物和非活性体系上，以提供有利于仿生功能和细胞调节的纳米视觉拓扑结构。 所得表面纳米级薄，纳米级分散，提供系统化学，表面积，表面体积，表面拓扑，基本上不含杂质，通过选择组成，R基团，纳米结构尺寸和拓扑结构具有可控性。 高度形状的特定和化学可裁剪的纳米结构分子的大小适合生物材料尺寸，并与所有灭菌方法兼容。

公开(公告)号：US07572872B2

公开(公告)日：2009-08-11

申请号：US11379993

申请日：2006-04-24

申请人： Jason T. Flodin ,  Joseph D. Lichtenhan ,  Joseph J. Schwab ,  Yi-Zhong An ,  Xuan Fu ,  Zachary Kemp

发明人： Jason T. Flodin ,  Joseph D. Lichtenhan ,  Joseph J. Schwab ,  Yi-Zhong An ,  Xuan Fu ,  Zachary Kemp

IPC分类号： C08F30/08

CPC分类号： A61L27/18 ,  A61L2400/12 ,  C08L83/04

摘要： Nanostructured chemicals such as polyhedral oligomeric silsesquioxanes, polyhedral oligomeric silicates, and polyhedral oligomeric metallasesquioxanes are attached to living and nonliving systems as biomaterials to provide a nanoscopic topology that favors biomimetic function and cellular modulation. The resulting surface is nanoscopically thin, nanoscopically dispersed, provides systematic chemistry, surface area, surface volume, surface topology, and is essentially free of impurities, and has controllable properties through selection of composition, R groups, nanostructure size and topology. Highly shape specific and chemically tailorable nanostructured molecules are sized to biological material dimensions and are compatible with all sterilization methods.

摘要翻译： 纳米结构化学物质​​如多面体低聚倍半硅氧烷，多面体低聚硅酸盐和多面体低聚金属氧化物倍半硅氧烷作为生物材料连接到生物和非活性体系上，以提供有利于仿生功能和细胞调节的纳米视觉拓扑结构。 所得表面纳米级薄，纳米级分散，提供系统化学，表面积，表面体积，表面拓扑，基本上不含杂质，通过选择组成，R基团，纳米结构尺寸和拓扑结构具有可控性。 高度形状的特定和化学可裁剪的纳米结构分子的大小适合生物材料尺寸，并与所有灭菌方法兼容。

公开(公告)号：US20060142512A1

公开(公告)日：2006-06-29

申请号：US11221356

申请日：2005-09-07

申请人： John Pojman ,  Brian McFarland ,  Zachary Kemp ,  Sam Popwell

发明人： John Pojman ,  Brian McFarland ,  Zachary Kemp ,  Sam Popwell

IPC分类号： C08F4/04

CPC分类号： C08F222/1006

摘要： A polymerization composition is formed by mixing a monomer polymerizable by frontal polymerization and an encapsulated, free-radical initiator which can be released by the application of heat. In a second embodiment, the monomer is also encapsulated.

摘要翻译： 通过将通过正面聚合可聚合的单体和可以通过加热释放的封装的自由基引发剂混合来形成聚合组合物。 在第二个实施方案中，单体也被包封。