公开(公告)号：US09493502B2

公开(公告)日：2016-11-15

申请号：US13981694

申请日：2012-01-20

申请人： Hongguang Du ,  Guocheng Liu ,  Zhongren Ding ,  Shuming Wang

发明人： Hongguang Du ,  Guocheng Liu ,  Zhongren Ding ,  Shuming Wang

IPC分类号： C07H19/167 ,  A61K31/7076 ,  C07H19/16

CPC分类号： C07H19/16 ,  A61K31/7076 ,  C07H19/167

摘要： The present invention relates to the compounds of the formulae (I) and (I-1) and the process for preparing the same, uses of the compounds for the treatment of diseases associated with platelet aggregation and in the manufacture of a medicament for the treatment of diseases associated with platelet aggregation, and relates to a pharmaceutical composition and a pharmaceutical formulation containing the compounds, wherein the definitions of R1, R2, R3 and R2a in the formulae are the same as those in the description.

公开(公告)号：US20140005138A1

公开(公告)日：2014-01-02

申请号：US13981694

申请日：2012-01-20

申请人： Hongguang Du ,  Guocheng Liu ,  Zhongren Ding ,  Shuming Wang

发明人： Hongguang Du ,  Guocheng Liu ,  Zhongren Ding ,  Shuming Wang

IPC分类号： C07H19/16

CPC分类号： C07H19/16 ,  A61K31/7076 ,  C07H19/167

摘要： The present invention relates to the compounds of the formulae (I) and (I-1) and the process for preparing the same, uses of the compounds for the treatment of diseases associated with platelet aggregation and in the manufacture of a medicament for the treatment of diseases associated with platelet aggregation, and relates to a pharmaceutical composition and a pharmaceutical formulation containing the compounds, wherein the definitions of R1, R2, R3 and R2a in the formulae are the same as those in the description.

摘要翻译： 本发明涉及式（I）和（I-1）的化合物及其制备方法，该化合物用于治疗与血小板聚集有关的疾病的用途以及制备用于治疗的药物 涉及与血小板聚集有关的疾病，涉及含有该化合物的药物组合物和药物制剂，其中式中R1，R2，R3和R2a的定义与说明书中相同。