专利检索 ap:"c/o Zymeworks BC Inc." 第 1 页

1.

发明授权
Methods of using a bispecific antigen-binding construct targeting HER2 in combination with CDK4/6 inhibitors for the treatment of breast cancer 有权

公开(公告)号：US12076400B2

公开(公告)日：2024-09-03

申请号：US16887460

申请日：2020-05-29

申请人： c/o Zymeworks BC Inc.

发明人： Nina E. Weisser , Diana F. Hausman , Patrick Kaminker

IPC分类号： A61K39/395 , A61K31/519 , A61K31/7068 , A61K33/243 , A61K47/68

CPC分类号： A61K39/3955 , A61K31/519 , A61K31/7068 , A61K33/243 , A61K47/6817

摘要： Described herein is a method of treating breast cancer comprising administering a bispecific antigen-binding construct targeting HER2 or a bispecific antigen-binding construct targeting HER2 linked to an auristatin analogue (ADC) in combination with a CDK4/6 inhibitor to a subject.