公开(公告)号：US20200263232A1

公开(公告)日：2020-08-20

申请号：US16530930

申请日：2019-08-02

Applicant: 10X GENOMICS, INC.

Inventor： Jason Bell ,  Josephine Lee ,  Corey Nemec ,  Francesca Meschi

IPC: C12Q1/6806 ,  C12N9/12 ,  C12N15/10

Abstract: Methods and compositions to minimize barcode exchange during the preparation of barcoded next-generation sequencing libraries prepared from a single cell. The methods utilize oligonucleotides containing a 3′-terminated blocking group or sequences that prevent amplification or extension.

公开(公告)号：US20250115946A1

公开(公告)日：2025-04-10

申请号：US18926858

申请日：2024-10-25

Applicant: 10x Genomics, Inc.

Inventor： Jason Bell ,  Josephine Lee ,  Corey Nemec ,  Francesca Meschi

IPC: C12Q1/6806 ,  C12N9/12 ,  C12N15/10

Abstract: Methods and compositions to minimize barcode exchange during the preparation of barcoded next-generation sequencing libraries prepared from a single cell. The methods utilize oligonucleotides containing a 3′-terminated blocking group or sequences that prevent amplification or extension.

公开(公告)号：US12163179B2

公开(公告)日：2024-12-10

申请号：US16530930

申请日：2019-08-02

Applicant: 10X GENOMICS, INC.

Inventor： Jason Bell ,  Josephine Lee ,  Corey Nemec ,  Francesca Meschi

IPC: C12Q1/6806 ,  C12N9/12 ,  C12N15/10

Abstract: Methods and compositions to minimize barcode exchange during the preparation of barcoded next-generation sequencing libraries prepared from a single cell. The methods utilize oligonucleotides containing a 3′-terminated blocking group or sequences that prevent amplification or extension.