公开(公告)号：US20220008364A1

公开(公告)日：2022-01-13

申请号：US17283471

申请日：2019-10-08

Applicant: AALTO UNIVERSITY FOUNDATION SR

Inventor： Christopher JONKERGOUW ,  Kodiah BEYEH ,  Ekaterina OSMEKHINA ,  Robin RAS ,  Markus LINDER

IPC: A61K31/14 ,  A61P31/04 ,  A61K31/4188 ,  A61K31/357

Abstract: This invention relates to macrocyclic cavity containing compounds and uses thereof in inhibiting a microbial signalling molecule or in reducing the amount of a microbial signalling molecule in a subject. The invention also relates to methods for inhibiting a microbial signalling molecule or for reducing the amount of a microbial signalling molecule in a subject by contacting a macrocyclic cavity-containing compound with said subject.