公开(公告)号：US20240336702A1

公开(公告)日：2024-10-10

申请号：US18743295

申请日：2024-06-14

Applicant: AB STUDIO INC.

Inventor： Yue Liu ,  Wenyan Cai ,  Jiadong Shi

IPC: C07K16/46 ,  A61K39/00 ,  A61P35/00 ,  C07K16/28

CPC classification number: C07K16/468 ,  A61P35/00 ,  C07K16/2809 ,  C07K16/2827 ,  C07K16/2896 ,  A61K2039/505

Abstract: This disclosure relates to bispecific antibodies or antigen-binding fragments thereof, wherein the bispecific antibodies or antigen-binding fragments thereof specifically bind to two different antigens with different binding affinities.

公开(公告)号：US20210206882A1

公开(公告)日：2021-07-08

申请号：US16635878

申请日：2018-08-01

Applicant: AB STUDIO INC.

Inventor： Yue Liu ,  Wenyan Cai ,  Jiadong Shi

IPC: C07K16/46 ,  C07K16/28 ,  A61P35/00

Abstract: This disclosure relates to bispecific antibodies or antigen-binding fragments thereof, wherein the bispecific antibodies or antigen-binding fragments thereof specifically bind to two different antigens with different binding affinities.

公开(公告)号：US20220017641A1

公开(公告)日：2022-01-20

申请号：US17398807

申请日：2021-08-10

Applicant: AB STUDIO INC.

Inventor： Yue Liu ,  Wenyan Cai ,  Jiadong Shi

IPC: C07K16/46 ,  A61P35/00 ,  C07K16/28

Abstract: This disclosure relates to bispecific antibodies or antigen-binding fragments thereof, wherein the bispecific antibodies or antigen-binding fragments thereof specifically bind to two different antigens with different binding affinities.

公开(公告)号：US11440972B2

公开(公告)日：2022-09-13

申请号：US17398853

申请日：2021-08-10

Applicant: AB STUDIO INC.

Inventor： Yue Liu ,  Wenyan Cai ,  Jiadong Shi

IPC: C07K16/46 ,  C07K16/28 ,  A61P35/00 ,  A61K39/00

Abstract: This disclosure relates to bispecific antibodies or antigen-binding fragments thereof, wherein the bispecific antibodies or antigen-binding fragments thereof specifically bind to two different antigens with different binding affinities.

公开(公告)号：US12049517B2

公开(公告)日：2024-07-30

申请号：US16635878

申请日：2018-08-01

Applicant: AB STUDIO INC.

Inventor： Yue Liu ,  Wenyan Cai ,  Jiadong Shi

IPC: C07K16/46 ,  A61P35/00 ,  C07K16/28 ,  A61K39/00

CPC classification number: C07K16/468 ,  A61P35/00 ,  C07K16/2809 ,  C07K16/2827 ,  C07K16/2896 ,  A61K2039/505

Abstract: This disclosure relates to bispecific antibodies or antigen-binding fragments thereof, wherein the bispecific antibodies or antigen-binding fragments thereof specifically bind to two different antigens with different binding affinities.

公开(公告)号：US11566083B2

公开(公告)日：2023-01-31

申请号：US17398807

申请日：2021-08-10

Applicant: AB STUDIO INC.

Inventor： Yue Liu ,  Wenyan Cai ,  Jiadong Shi

IPC: A61P35/00 ,  C07K16/28 ,  C07K16/46 ,  A61K39/00

Abstract: This disclosure relates to bispecific antibodies or antigen-binding fragments thereof, wherein the bispecific antibodies or antigen-binding fragments thereof specifically bind to two different antigens with different binding affinities.

公开(公告)号：US20220025072A1

公开(公告)日：2022-01-27

申请号：US17398853

申请日：2021-08-10

Applicant: AB STUDIO INC.

Inventor： Yue Liu ,  Wenyan Cai ,  Jiadong Shi

IPC: C07K16/46 ,  A61P35/00 ,  C07K16/28

Abstract: This disclosure relates to bispecific antibodies or antigen-binding fragments thereof, wherein the bispecific antibodies or antigen-binding fragments thereof specifically bind to two different antigens with different binding affinities.

公开(公告)号：US20210163547A1

公开(公告)日：2021-06-03

申请号：US17145870

申请日：2021-01-11

Applicant: Ab Studio Inc.

Inventor： Yue Liu ,  Jiadong Shi

IPC: C07K14/31 ,  C12N9/24 ,  G01N33/533 ,  G01N33/68

Abstract: A composition for charactering an internalizing antibody is provided. The composition includes an antibody-binding moiety and a detectable agent.