公开(公告)号：US20170304565A1

公开(公告)日：2017-10-26

申请号：US15517579

申请日：2015-10-09

申请人： ABLYNX N.V. ,  VECTURA GMBH

发明人： Koen ALLOSERY ,  Martin HUBER ,  Tobias KOLB ,  Bernhard MÜLLINGER ,  Juliane SCHICK ,  Erik DEPLA

IPC分类号： A61M15/00 ,  C07K16/10 ,  A61M15/02

摘要： An inhalation device, assembly or system can include a kit and a pharmaceutical composition. The device can be adapted for administering therapeutic aerosols to pediatric patients, including neonates, infants or toddlers. The device can further include a vibrating mesh aerosol generator that can be insertable into a flow channel of the inhalation device through a lateral opening, and a valved face mask. The device can be connectable to a gas source through which a gas, such as oxygen, can be received into the flow channel at a low flow rate.

公开(公告)号：US20170304566A1

公开(公告)日：2017-10-26

申请号：US15517693

申请日：2015-10-09

申请人： ABLYNX N.V. ,  VECTURA GMBH

发明人： Koen ALLOSERY ,  Erik DEPLA ,  Martin HUBER ,  Tobias KOLB ,  Bernhard MÜLLINGER ,  Massimiliano GERMANI ,  Juliane SCHICK ,  Maria-Laura SARGENTINI

IPC分类号： A61M15/00 ,  A61K9/00 ,  A61K39/42 ,  A61K45/06 ,  C07K16/10 ,  A61M15/02 ,  A61K39/00

摘要： Methods are provided for the treatment of RSV infections in young children. More specifically, methods are provided wherein polypeptides that bind F protein of hRSV and that neutralize RSV infection are administered to the lungs of young children at specific dose regimens.