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公开(公告)号：US11619831B2
公开(公告)日：2023-04-04
申请号：US17806326
申请日：2022-06-10
申请人： ACUCELA INC.
发明人： Beat Wyss , Jean-Noël Fehr , Glenn Noronha , Karim Haroud , Julien Sauvet , Hans Bernhard , Christian Oggenfuss , Amitava Gupta , Ryo Kubota
摘要： A soft contact lens comprises a plurality of light sources coupled to a plurality of optical elements. The plurality of light sources and the plurality of optical elements are embedded in a soft contact lens material. Each of said plurality of optical elements generates an image focused in front of a peripheral retina of a wearer. In some embodiments, each of the images is focused at a distance in front of the peripheral retina at a location, and each of the images comprises a depth of focus and a spatial resolution. The depth of focus can be less than the distance, and the spatial resolution greater than a spatial resolution of the peripheral retina at the location.
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公开(公告)号：US11480813B2
公开(公告)日：2022-10-25
申请号：US17650134
申请日：2022-02-07
申请人： ACUCELA INC.
发明人： Ryo Kubota , Nabin Joshi , Arkady Selenow , Steven Ali , Stefan Bauer , Jean-Noël Fehr , Moritz Haeberli , Patrizia Weber , Julien Sauvet , Amitava Gupta
摘要： An apparatus to treat refractive error of the eye comprises one or more optics configured to project stimuli comprising out of focus images onto the peripheral retina outside the macula. While the stimuli can be configured in many ways, in some embodiments the stimuli are arranged to decrease interference with central vison such as macular vision. The stimuli can be out of focus images may comprise an amount of defocus within a range from about 3 Diopters (“D”) to about 6 D. In some embodiments, the brightness of the stimuli is greater than a brightness of background illumination by an appropriate amount such as at least 3 times the background brightness. In some embodiments, each of a plurality of stimuli comprises a spatial frequency distribution with an amplitude profile having spatial frequencies within a range from about range of 1×10−1 to 2.5×101 cycles per degree.
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公开(公告)号：US11275259B2
公开(公告)日：2022-03-15
申请号：US17304691
申请日：2021-06-24
申请人： ACUCELA INC.
发明人： Ryo Kubota , Nabin Joshi , Arkady Selenow , Steven Ali , Stefan Bauer , Jean-Noël Fehr , Moritz Haeberli , Patrizia Weber , Julien Sauvet , Amitava Gupta
摘要： An apparatus to treat refractive error of the eye comprises one or more optics configured to project stimuli comprising out of focus images onto the peripheral retina outside the macula. While the stimuli can be configured in many ways, in some embodiments the stimuli are arranged to decrease interference with central vison such as macular vision. The stimuli can be out of focus images may comprise an amount of defocus within a range from about 3 Diopters (“D”) to about 6 D. In some embodiments, the brightness of the stimuli is greater than a brightness of background illumination by an appropriate amount such as at least 3 times the background brightness. In some embodiments, each of a plurality of stimuli comprises a spatial frequency distribution with an amplitude profile having spatial frequencies within a range from about range of 1×10−1 to 2.5×101 cycles per degree.
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4.发明授权公开(公告)号：US11733545B2
公开(公告)日：2023-08-22
申请号：US17753773
申请日：2020-09-15
申请人： ACUCELA INC.
发明人： Ryo Kubota , Jean-Noël Fehr , Hans Bernhard , Patrizia Weber , Alain Saurer , Amitava Gupta
CPC分类号： G02C7/047 , G02C11/04 , G02C11/10 , G02C2202/24
摘要： An opto-electronic module is configured to fit between anterior and posterior surfaces of a contact lens. The opto-electronics module may comprise a plurality of light sources configured to direct a plurality of light beams to a region of the retina away from the fovea and in some embodiments away from the macula. Each of the plurality of light sources may comprises an LED and one or more projection optics. Each of the projection optics can be coupled to an LED with an adhesive prior to placing the opto-electronics module on a layer of contact lens material. The opto-electronics module may comprise a flex PCB with the plurality of light sources, an antenna, a battery, a capacitor and a processor supported on the flex PCB.
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公开(公告)号：US11583696B2
公开(公告)日：2023-02-21
申请号：US17662098
申请日：2022-05-05
申请人： ACUCELA INC.
发明人： Ryo Kubota , Karim Haroud , Beat Wyss , Hans Bernhard , Jean-Noël Fehr , Patrizia Weber , Moritz Haeberli , Amitava Gupta
摘要： A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.
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公开(公告)号：US11358001B2
公开(公告)日：2022-06-14
申请号：US16947537
申请日：2020-08-05
申请人： ACUCELA INC.
发明人： Ryo Kubota , Karim Haroud , Beat Wyss , Hans Bernhard , Jean-Noël Fehr , Patrizia Weber , Moritz Haeberli , Amitava Gupta
摘要： A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.
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