公开(公告)号：US20210301348A1

公开(公告)日：2021-09-30

申请号：US15999597

申请日：2017-02-16

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Patrick TAN ,  Aditi QAMRA ,  Manjie XING ,  Wen Fong OOI

IPC: C12Q1/6886

Abstract: The present invention relates to a method for determining the presence or absence of at least one promoter in a cancerous biological sample relative to a non-cancerous biological sample. The present invention also relates to a method for determining the prognosis of cancer in a subject, a method for modulating the activity of at least one cancer-associated promoter in a cell, a method for modulating the immune response of a subject to cancer, a method for determining the presence of at least one cancer-associated promoter in a cancerous biological sample relative to a non-cancerous biological sample and a biomarker for detecting cancer in a subject.

公开(公告)号：US20160355886A1

公开(公告)日：2016-12-08

申请号：US15108012

申请日：2014-12-30

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Boon Ooi Patrick TAN ,  Masafumi MURATANI ,  Aditi QAMRA

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/158

Abstract: The present invention is directed to methods for determining the activity of a promoter. The present invention further describes a method for determining the susceptibility of a subject to cancer and biomarkers for detecting cancer in a subject.

Abstract translation: 本发明涉及确定启动子活性的方法。 本发明还描述了一种用于确定受试者对癌症的敏感性和用于检测受试者中癌症的生物标志物的方法。