公开(公告)号：US20220133883A1

公开(公告)日：2022-05-05

申请号：US17576800

申请日：2022-01-14

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Madhavan NALLANI ,  Fabien DECAILLOT ,  Zhikang FU ,  Xingfang SU

IPC: A61K39/385 ,  A61K9/127 ,  A61K9/00 ,  A61K47/34 ,  A61K39/12

Abstract: The invention relates to methods for eliciting an immune response to an immunogen, and in particular, to such methods using polymersomes as carriers for the immunogen.

公开(公告)号：US20190322864A1

公开(公告)日：2019-10-24

申请号：US16457920

申请日：2019-06-28

Applicant: Agency for Science, Technology and Research

Inventor： Madhavan NALLANI ,  Eva-Kathrin SINNER ,  Madanagopal KUNNAVAKKAM

IPC: C08L71/02 ,  C08G65/329

Abstract: Disclosed is a vesicular system comprising a surface with a vesicle immobilized thereon. The immobilized vesicle has a circumferential membrane of an amphiphilic polymer. The vesicle is coupled to a surface by means of a molecule with a non-polar moiety. The non-polar moiety comprises a main chain of 3 to about 30 carbon atoms and 0 to about 12 heteroatoms selected from Si, O, S, and Se. The molecule with the non-polar moiety is coupled to the surface via a covalent or non-covalent bond. A portion of the non-polar moiety is integrated in the circumferential membrane.