专利检索 ap:("AGENUS INC." OR "LUDWIG INSTITUTE FOR CANCER RESEARCH LTD" OR "MEMORIAL SLOAN KETTERING CANCER CENTER") AND inv:"TAHA MERGHOUB" 第 1 页

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发明申请
ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20190256601A1

公开(公告)日：2019-08-22

申请号：US16399262

申请日：2019-04-30

申请人： AGENUS INC. , LUDWIG INSTITUTE FOR CANCER RESEARCH LTD , MEMORIAL SLOAN KETTERING CANCER CENTER

发明人： MARC VAN DIJK , CORNELIA ANNE MUNDT , GERD RITTER , JEDD DAVID WOLCHOK , TAHA MERGHOUB , ROBERTA ZAPPASODI , RIKKE BAEK HOLMGAARD , DAVID SCHAER , DAVID ADAM SAVITSKY , NICHOLAS STUART WILSON

IPC分类号： C07K16/28

摘要： The instant disclosure provides antibodies that specifically bind to human PD-1 and antagonize PD-1 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.