专利检索 ap:("AGENUS INC." OR "LUDWIG INSTITUTE FOR CANCER RESEARCH LTD." OR "MEMORIAL SLOAN-KETTERING CANCER CENTER") AND inv:"Rikke Baek HOLMGAARD" 第 1 页

1.

发明申请
ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF 有权

公开(公告)号：US20220372149A1

公开(公告)日：2022-11-24

申请号：US17662518

申请日：2022-05-09

申请人： AGENUS INC. , LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. , MEMORIAL SLOAN-KETTERING CANCER CENTER

发明人： Marc VAN DIJK , Cornelia Anne MUNDT , Gerd RITTER , Jedd David WOLCHOK , Taha MERGHOUB , Roberta ZAPPASODI , Rikke Baek HOLMGAARD , David SCHAER , David Adam SAVITSKY , Nicholas Stuart WILSON

IPC分类号： C07K16/28 , A61P35/00 , A61K45/06 , A61K39/395

摘要： The instant disclosure provides antibodies that specifically bind to human PD-1 and antagonize PD-1 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.