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公开(公告)号:US20220064323A1
公开(公告)日:2022-03-03
申请号:US17476650
申请日:2021-09-16
Applicant: AIMM Therapeutics B.V.
Inventor: Hergen SPITS , Paula Maria Wilhelmina VAN HELDEN , Remko SCHOTTE , Wouter POS , Christien FATMAWATI , Danïel Michiel GO , Koen WAGNER , Julien Christian VILLAUDY
IPC: C07K16/28 , A61P35/00 , C07K14/705 , G01N33/574
Abstract: The present invention provides novel binding compounds and therapeutic applications thereof.
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公开(公告)号:US20170008952A1
公开(公告)日:2017-01-12
申请号:US15113563
申请日:2015-01-30
Applicant: AIMM THERAPEUTICS B.V
Inventor: Mark Jeroen KWAKKENBOS , Koen WAGNER , Adrianus Quirinus BAKKER
CPC classification number: C07K16/1018 , C07K16/00 , C07K2317/14 , C07K2317/21 , C07K2317/33 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12Q1/6869
Abstract: The invention provides means and methods for selecting and producing stable antibodies against an antigen of interest, using stable ex vivo B cell cultures.
Abstract translation: 本发明提供了使用稳定的离体B细胞培养物选择和产生针对感兴趣抗原的稳定抗体的方法和方法。
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公开(公告)号:US20190023803A1
公开(公告)日:2019-01-24
申请号:US16068742
申请日:2017-01-06
Applicant: AIMM Therapeutics B.V.
Inventor: Hergen SPITS , Paula Maria Wilhelmina VAN HELDEN , Remko SCHOTTE , Wouter POS , Christien FATMAWATI , Danïel Michiel GO , Koen WAGNER , Julien Christian VILLAUDY
IPC: C07K16/28 , C07K14/705 , G01N33/574 , A61P35/00
Abstract: The present invention provides novel binding compounds and therapeutic applications thereof.
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4.
公开(公告)号:US20160096881A1
公开(公告)日:2016-04-07
申请号:US14956919
申请日:2015-12-02
Applicant: AIMM THERAPEUTICS B.V.
Inventor: Tim BEAUMONT , Mark Jeroen KWAKKENBOS , Hergen SPITS , Adrianus Quirinus BAKKER , Koen WAGNER
IPC: C07K16/10
CPC classification number: C07K16/1018 , C07K14/4703 , C07K14/4747 , C07K16/00 , C07K2317/21 , C07K2317/565 , C07K2317/92
Abstract: The invention provides means and methods for producing high-affinity antibodies against an antigen of interest, usually stable B-cell cultures.
Abstract translation: 本发明提供了用于产生针对感兴趣的抗原(通常是稳定的B细胞培养物)的高亲和力抗体的方法和方法。
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