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公开(公告)号：US10081648B2
公开(公告)日：2018-09-25
申请号：US14898355
申请日：2014-06-13
发明人： Shiladitya Sengupta , Monideepa Roy , Arindam Sarkar , SK Samad Hossain , Aniruddha Sengupta , Pradip Kumar Dutta , Aasif Ansari , Swadhin K. Mandal
CPC分类号： C07F15/0093 , C07F15/0086 , C07H23/00 , C07J41/0055
摘要： The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to platinum based compounds comprising platinum moiety, linker moiety and lipid moiety and corresponding nanoparticles thereof. The disclosure further relates to synthesis of said platinum based compounds, nanoparticles and compositions comprising said platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by employing aforesaid carbene compounds, platinum based compounds, nanoparticles and compositions thereof.
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公开(公告)号：US10730899B2
公开(公告)日：2020-08-04
申请号：US16123430
申请日：2018-09-06
发明人： Shiladitya Sengupta , Monideepa Roy , Arindam Sarkar , SK Samad Hossain , Aniruddha Sengupta , Pradip Dutta , Aasif Ansari
摘要： The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to platinum based compounds comprising platinum moiety, linker moiety and lipid moiety and corresponding nanoparticles thereof. The disclosure further relates to synthesis of said platinum based compounds, nanoparticles and compositions comprising said platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by employing aforesaid carbene compounds, platinum based compounds, nanoparticles and compositions thereof.
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公开(公告)号：US20190002489A1
公开(公告)日：2019-01-03
申请号：US16123430
申请日：2018-09-06
发明人： Shiladitya SENGUPTA , Monideepa Roy , Arindam Sarkar , Sk Samad Hossain , Aniruddha Sengupta , Pradip Kumar Dutta , Aasif Ansari
摘要： The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to platinum based compounds comprising platinum moiety, linker moiety and lipid moiety and corresponding nanoparticles thereof. The disclosure further relates to synthesis of said platinum based compounds, nanoparticles and compositions comprising said platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by employing aforesaid carbene compounds, platinum based compounds, nanoparticles and compositions thereof.
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公开(公告)号：US11358978B2
公开(公告)日：2022-06-14
申请号：US15575090
申请日：2016-05-18
发明人： Nimish Gupta , Arindam Sarkar , Heeralal Bassi , Pradip Dutta
摘要： The present invention is in relation to the fields of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to improved methods for preparing lipid-conjugated platinum compounds with high purity and good yields. The present disclosure also relates to nanoparticles comprising lipid-conjugated platinum compounds with high drug loading efficiency for use in chemotherapy, and to methods for producing said nanoparticles.
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