公开(公告)号：US20210101965A1

公开(公告)日：2021-04-08

申请号：US17001604

申请日：2020-08-24

Applicant: ALLERGAN, INC. ,  XENCOR, INC.

Inventor： Peter C. BACIU ,  Yanbin LIANG ,  Jason GUU ,  Matthew BERNETT ,  Umesh MUCHHAL ,  John DESJARLAIS

IPC: C07K16/18 ,  A61K39/00 ,  A61K39/395

Abstract: The present disclosure relates to antibodies and polynucleotides encoding the same, that may be used to prevent, control, or reduce the activity of the complement pathway. In addition, the disclosure is directed to compositions and methods for diagnosing and treating diseases mediated by or involving complement C5. Specifically, the disclosure is related to C5 antibodies.