-
公开(公告)号:US20230136787A1
公开(公告)日:2023-05-04
申请号:US17798156
申请日:2021-02-09
发明人: JAMES D. MCININCH , MARK KEATING , MARK K. SCHLEGEL , ADAM CASTORENO , VASANT R. JADHAV , CHARALAMBOS KAITTANIS , ELENA CASTELLANOS-RIZALDOS , BHAUMIK A. PANDYA
IPC分类号: C12N15/113 , A61P27/02 , A61K45/06
摘要: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting VEGF-A, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of VEGF-A.
-
公开(公告)号:US20240318175A1
公开(公告)日:2024-09-26
申请号:US18572486
申请日:2022-06-28
发明人: ADAM CASTORENO , BHAUMIK A. PANDYA , ELENA CASTELLANOS-RIZALDOS , MARK K. SCHLEGEL , VASANT R. JADHAV
IPC分类号: C12N15/113 , A61K9/00 , A61K45/06 , A61P27/06
CPC分类号: C12N15/113 , A61K9/0048 , A61K45/06 , A61P27/06 , C12N2310/11 , C12N2310/3125 , C12N2310/313 , C12N2310/3513 , C12N2310/3515 , C12N2310/533 , C12N2320/32
摘要: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting MYOC, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of MYOC.
-