公开(公告)号：US20220090133A1

公开(公告)日：2022-03-24

申请号：US17435768

申请日：2020-03-03

Applicant: AMGEN INC.

Inventor： Jason James DEVOSS ,  Walter Hans MEISEN ,  Christine Elaine TINBERG ,  Keegan COOKE ,  Achim Klaus MOESTA

IPC: C12N15/86 ,  C12N7/00 ,  C07K14/54 ,  C07K14/71 ,  A61P35/00 ,  A61K38/20 ,  A61K38/17

Abstract: The present invention relates to the use of oncolytic viruses (e.g., modified HSV-1 viruses) for the treatment of various types of cancer. In addition, the present invention relates to compositions and kits relating to such uses of oncolytic viruses.