公开(公告)号：US11986624B2

公开(公告)日：2024-05-21

申请号：US16489833

申请日：2018-03-09

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Erich Coiner ,  Alan D. Payne

IPC: A61M5/142

CPC classification number: A61M5/14248 ,  A61M2005/14252

Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.

公开(公告)号：US11369736B2

公开(公告)日：2022-06-28

申请号：US16485245

申请日：2018-02-13

Applicant: AMGEN INC.

Inventor： Erich Coiner ,  Paul Faucher ,  Adam B. McCullough ,  Antonio Ubach

IPC: A61M5/142 ,  A61M5/158 ,  A61B17/34

Abstract: An insertion mechanism for a wearable drug delivery device that deploys a small gauge flexible cannula with support of a coaxial rigid trocar or hollow needle. After insertion, the trocar or hollow needle is withdrawn leaving the cannula in place for drug delivery. The insertion mechanism may also include an insertion mechanism housing having a proximal and distal end, a manifold configured to fluidly connect the hollow interior of the cannula and the fluid pathway connector, and a manifold guide carrying the manifold and movable between a first position and a second position. A hub carries the trocar and is removably connected to the manifold guide. An insertion biasing member may be initially retained in an energized state between the proximal end of the insertion mechanism housing and the hub, and a retraction biasing member may be initially retained in an energized state between the hub and the manifold guide.

公开(公告)号：US20200023122A1

公开(公告)日：2020-01-23

申请号：US16489833

申请日：2018-03-09

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Erich Coiner ,  Alan D. Payne

IPC: A61M5/142

Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.

公开(公告)号：US20240382673A1

公开(公告)日：2024-11-21

申请号：US18642384

申请日：2024-04-22

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Erich Coiner ,  Alan D. Payne

IPC: A61M5/142

Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.

公开(公告)号：US11464900B2

公开(公告)日：2022-10-11

申请号：US17099137

申请日：2020-11-16

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Erich Coiner ,  Alan D. Payne

IPC: A61M5/142

Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.

公开(公告)号：US20210077713A1

公开(公告)日：2021-03-18

申请号：US17099137

申请日：2020-11-16

Applicant: AMGEN INC,

Inventor： Adam B. McCullough ,  Erich Coiner ,  Alan D. Payne

IPC: A61M5/142

Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.