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公开(公告)号：US20220289807A1
公开(公告)日：2022-09-15
申请号：US17634685
申请日：2020-08-13
Applicant: AMGEN INC.
Inventor： Darren L. BATES , Sue J. SOHN , Hannah Beth CATTERALL , Zhulun WANG
Abstract: Provided herein are IL-2 muteins and IL-2 mutein Fc fusion molecules that preferentially expand and activate cells and are amenable to large scale production. Also provided herein are methods of making and using the compositions of the present invention.
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