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公开(公告)号：US11738138B2
公开(公告)日：2023-08-29
申请号：US16819443
申请日：2020-03-16
Applicant: AMGEN INC.
Inventor： Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV
CPC classification number: A61M5/14248 , A61M5/14244 , A61M5/158 , A61M5/3287 , A61M2005/14252 , A61M2005/1583 , A61M2005/1585 , A61M2205/13 , A61M2205/18 , A61M2205/44 , A61M2205/581 , A61M2205/583 , A61M2207/00
Abstract: An insertion mechanism for a drug pump includes an insertion mechanism housing; a sleeve; a rotational biasing member initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the sleeve. The needle is inserted into a target tissue by the rotational biasing member and interaction between the hub and housing. Retraction of the needle is caused by decompressing or de-energizing of the retraction biasing member. A drug delivery pump includes an activation mechanism, a drive mechanism, a sterile access connection, and the insertion mechanism. Assembly and operation methods are provided.
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公开(公告)号：US11129936B2
公开(公告)日：2021-09-28
申请号：US16089685
申请日：2017-04-07
Applicant: AMGEN INC.
Inventor： Scott R. Gibson , Sheldon B. Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Antonio Ubach , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Ian P. Dardani , Sean M. O'connor , Danielle Feldman
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device includes a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector defines a sterile fluid flowpath between the container and the insertion mechanism. A cannula initially disposed about the needle is included.
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公开(公告)号：US12201809B2
公开(公告)日：2025-01-21
申请号：US17386659
申请日：2021-07-28
Applicant: AMGEN INC.
Inventor： Scott R. Gibson , Sheldon B. Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Antonio Ubach , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Ian P. Dardani , Sean M. O'connor , Danielle Feldman
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.
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公开(公告)号：US20230270934A1
公开(公告)日：2023-08-31
申请号：US18144360
申请日：2023-05-08
Applicant: AMGEN INC.
Inventor： Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV
CPC classification number: A61M5/14248 , A61M5/14244 , A61M5/158 , A61M5/3287 , A61M2005/14252 , A61M2005/1583 , A61M2005/1585 , A61M2205/13 , A61M2205/18 , A61M2205/581 , A61M2205/583 , A61M2207/00
Abstract: An insertion mechanism for a drug pump includes an insertion mechanism housing; a sleeve; a rotational biasing member initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the sleeve. The needle is inserted into a target tissue by the rotational biasing member and interaction between the hub and housing. Retraction of the needle is caused by decompressing or de-energizing of the retraction biasing member. A drug delivery pump includes an activation mechanism, a drive mechanism, a sterile access connection, and the insertion mechanism. Assembly and operation methods are provided.
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公开(公告)号：US20220218900A1
公开(公告)日：2022-07-14
申请号：US17688578
申请日：2022-03-07
Applicant: AMGEN INC.
Inventor： Scott R. Gibson , Sheldon B, Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Sean M. O'connor , Robert Decker , Gautam N. Shetty , Ryan M. Agard , Nicholas J. Ciccarelli , Daniel Davenport
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.
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Patent Agency Ranking
公开(公告)号：US20200316291A1
公开(公告)日：2020-10-08
申请号：US16089685
申请日：2017-04-07
Applicant: AMGEN INC.
Inventor： Scott Robert Gibson , Sheldon B. Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Antonio Ubach , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Ian P. Dardani , Sean M. O'connor , Danielle Feldman
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device includes a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector defines a sterile fluid flowpath between the container and the insertion mechanism. A cannula initially disposed about the needle is included.
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公开(公告)号：US12208237B2
公开(公告)日：2025-01-28
申请号：US18144360
申请日：2023-05-08
Applicant: AMGEN INC.
Inventor： Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV
Abstract: An insertion mechanism for a drug pump includes an insertion mechanism housing; a sleeve; a rotational biasing member initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the sleeve. The needle is inserted into a target tissue by the rotational biasing member and interaction between the hub and housing. Retraction of the needle is caused by decompressing or de-energizing of the retraction biasing member. A drug delivery pump includes an activation mechanism, a drive mechanism, a sterile access connection, and the insertion mechanism. Assembly and operation methods are provided.
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公开(公告)号：US11266777B2
公开(公告)日：2022-03-08
申请号：US16071873
申请日：2017-02-13
Applicant: AMGEN INC.
Inventor： Scott R. Gibson , Sheldon B. Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Sean M. O'connor , Robert Decker , Gautam N. Shetty , Ryan M. Agard , Nicholas J. Ciccarelli , Daniel Davenport
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.
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公开(公告)号：US20210069410A1
公开(公告)日：2021-03-11
申请号：US16951893
申请日：2020-11-18
Applicant: AMGEN INC.
Inventor： Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV
Abstract: An insertion mechanism for a drug pump includes an insertion mechanism housing; a sleeve; a rotational biasing member initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the sleeve. The needle is inserted into a target tissue by the rotational biasing member and interaction between the hub and housing. Retraction of the needle is caused by decompressing or de-energizing of the retraction biasing member. A drug delivery pump includes an activation mechanism, a drive mechanism, a sterile access connection, and the insertion mechanism. Assembly and operation methods are provided.
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公开(公告)号：US11672905B2
公开(公告)日：2023-06-13
申请号：US16951893
申请日：2020-11-18
Applicant: AMGEN INC.
Inventor： Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV
CPC classification number: A61M5/14248 , A61M5/14244 , A61M5/158 , A61M5/3287 , A61M2005/14252 , A61M2005/1583 , A61M2005/1585 , A61M2205/13 , A61M2205/18 , A61M2205/44 , A61M2205/581 , A61M2205/583 , A61M2207/00
Abstract: An insertion mechanism for a drug pump includes an insertion mechanism housing; a sleeve; a rotational biasing member initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the sleeve. The needle is inserted into a target tissue by the rotational biasing member and interaction between the hub and housing. Retraction of the needle is caused by decompressing or de-energizing of the retraction biasing member. A drug delivery pump includes an activation mechanism, a drive mechanism, a sterile access connection, and the insertion mechanism. Assembly and operation methods are provided.
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