公开(公告)号：US20150218284A1

公开(公告)日：2015-08-06

申请号：US14618945

申请日：2015-02-10

Applicant: AMGEN INC.

Inventor： John M. DELANEY ,  William C. FANSLOW, III ,  Chadwick T. KING

IPC: C07K16/30 ,  A61K39/395 ,  A61K31/5365 ,  A61K47/48

CPC classification number: C07K16/30 ,  A61K31/5365 ,  A61K39/39558 ,  A61K47/6803 ,  A61K47/6849 ,  A61K47/6851 ,  A61K2039/505 ,  C07K16/2875 ,  C07K2317/21 ,  C07K2317/33 ,  C07K2317/56 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/76 ,  C07K2317/77 ,  C07K2317/92

Abstract: The present invention relates to CD27L antigen binding proteins, such an antibodies, polynucleotides encoding said CD27l antigen binding proteins, antibody drug conjugate compositions, and methods for diagnosing and treating diseases associated with CD27L expression.

Abstract translation: 本发明涉及CD27L抗原结合蛋白，如抗体，编码所述CD271抗原结合蛋白的多核苷酸，抗体药物共轭组合物，以及用于诊断和治疗与CD27L表达相关疾病的方法。