公开(公告)号：US10421824B2

公开(公告)日：2019-09-24

申请号：US15258750

申请日：2016-09-07

Applicant: Amgen Inc.

Inventor： Hailing Hsu ,  Ming Zhang ,  Gunasekaran Kannan ,  Frederick Jacobsen ,  Wayne Tsuji

IPC: C07K16/28 ,  A61K39/395 ,  C07K16/46 ,  A61K45/06 ,  A61K39/00

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

公开(公告)号：US10421823B2

公开(公告)日：2019-09-24

申请号：US14776399

申请日：2014-03-12

Applicant: AMGEN INC.

Inventor： Hailing Hsu ,  Ming Zhang ,  Gunasekaran Kannan ,  Frederick W. Jacobsen ,  Wayne Tsuji

IPC: C07K16/28 ,  C07K16/46 ,  A61K39/395 ,  A61P37/06 ,  C07K16/18 ,  C07K16/24 ,  A61P29/02 ,  A61P19/02 ,  A61K39/00

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

公开(公告)号：US11492417B2

公开(公告)日：2022-11-08

申请号：US16579321

申请日：2019-09-23

Applicant: AMGEN INC.

Inventor： Hailing Hsu ,  Ming Zhang ,  Gunasekaran Kannan ,  Frederick Jacobsen ,  Wayne Tsuji

IPC: C07K16/28 ,  C07K16/46 ,  A61P37/06 ,  A61P19/02 ,  A61P29/02 ,  A61K39/395 ,  C07K16/18 ,  C07K16/24 ,  A61K39/00

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

公开(公告)号：US20210206881A1

公开(公告)日：2021-07-08

申请号：US16579321

申请日：2019-09-23

Applicant: AMGEN INC.

Inventor： Hailing Hsu ,  Ming Zhang ,  Gunasekaran Kannan ,  Frederick Jacobsen ,  Wayne Tsuji

IPC: C07K16/46 ,  A61P37/06 ,  A61P19/02 ,  A61P29/02 ,  A61K39/395 ,  C07K16/28 ,  C07K16/18 ,  C07K16/24

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

公开(公告)号：US20170066845A1

公开(公告)日：2017-03-09

申请号：US15258750

申请日：2016-09-07

Applicant: Amgen Inc.

Inventor： Hailing Hsu ,  Ming Zhang ,  Gunasekaran Kannan ,  Frederick Jacobsen ,  Wayne Tsuji

IPC: C07K16/46 ,  A61K45/06 ,  A61K39/395 ,  C07K16/28

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

Abstract translation: 本文描述了对BAFF和B7RP1特异性的双特异性蛋白质，编码这种蛋白质的核酸，制备此类蛋白质的方法以及这些蛋白质的用途。

公开(公告)号：US09458246B2

公开(公告)日：2016-10-04

申请号：US14203123

申请日：2014-03-10

Applicant: Amgen Inc.

Inventor： Hailing Hsu ,  Ming Zhang ,  Gunasekaran Kannan ,  Frederick W. Jacobsen ,  Wayne Tsuji

IPC: C07K16/28 ,  C07K16/46 ,  A61K39/395 ,  A61K45/06 ,  A61K39/00

CPC classification number: C07K16/468 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/2827 ,  C07K16/2875 ,  C07K2317/31 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/94 ,  C07K2318/10 ,  C07K2319/70

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

Abstract translation: 本文描述了对BAFF和B7RP1特异性的双特异性蛋白质，编码这种蛋白质的核酸，制备此类蛋白质的方法以及这些蛋白质的用途。

公开(公告)号：US20160024225A1

公开(公告)日：2016-01-28

申请号：US14776399

申请日：2014-03-12

Applicant: AMGEN INC.

Inventor： Hailing Hsu ,  Ming Zhang ,  Gunasekaran Kannan ,  Frederick W. Jacobsen ,  Wayne Tsuji

IPC: C07K16/46 ,  C07K16/18 ,  C07K16/24

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

Abstract translation: 本文描述了对BAFF和B7RP1特异性的双特异性蛋白质，编码这种蛋白质的核酸，制备此类蛋白质的方法以及这些蛋白质的用途。