公开(公告)号：US20230128444A1

公开(公告)日：2023-04-27

申请号：US17936062

申请日：2022-09-28

Applicant: AMGEN INC.

Inventor： Hailing HSU ,  Ming ZHANG ,  Gunasekaran KANNAN ,  Frederick W. JACOBSEN ,  Wayne H. TSUJI

IPC: C07K16/46 ,  A61P37/06 ,  A61P19/02 ,  A61P29/02 ,  A61K39/395 ,  C07K16/28 ,  C07K16/18 ,  C07K16/24

Abstract: Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins.

公开(公告)号：US20180002417A1

公开(公告)日：2018-01-04

申请号：US15622990

申请日：2017-06-14

Applicant: Celimmune LLC ,  Amgen Inc.

Inventor： Francisco LEON ,  Wayne H. TSUJI

IPC: C07K16/24 ,  A61K39/00

CPC classification number: C07K16/243 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/545 ,  C07K16/244 ,  C07K2317/21 ,  C07K2317/56

Abstract: Methods and pharmaceutical compositions are provided herein for the treatment of inflammatory disorders, in particular celiac disease, refractory celiac disease and non-celiac gluten sensitivity.