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公开(公告)号：US20240409611A1
公开(公告)日：2024-12-12
申请号：US18817735
申请日：2024-08-28
Applicant: Amgen Inc.
Inventor： Yael WEXLER-COHEN , Robert Matthew FESINMEYER , Monica Michelle GOSS , Sekhar KANAPURAM , Rahul Rajan KAUSHIK , Sai Chakradhar PADALA
Abstract: VEGFR-Fc fusion protein formulations and methods of making using such formulations are provided herein. In one embodiment, the formulation is an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the VEGFR-Fc fusion protein is aflibercept.
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公开(公告)号：US20250082726A1
公开(公告)日：2025-03-13
申请号：US18959137
申请日：2024-11-25
Applicant: AMGEN INC.
Inventor： Yael WEXLER-COHEN , William J. CALLAHAN , Robert Matthew FESINMEYER , Rahul Rajan KAUSHIK , Sai Chakradhar PADALA
Abstract: Protein formulations and methods of making and using such formulations are provided herein. The formulation can be an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the formulation comprises a VEGFR-Fc fusion protein, such as aflibercept.
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Patent Agency Ranking
公开(公告)号：US20240415929A1
公开(公告)日：2024-12-19
申请号：US18822739
申请日：2024-09-03
Applicant: Amgen Inc.
Inventor： Yael WEXLER-COHEN , Robert Matthew FESINMEYER , Rahul Rajan KAUSHIK
Abstract: Protein formulations and methods of making and using such formulations are provided herein. The formulation can be an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the formulation comprises a VEGFR-Fc fusion protein, such as aflibercept. In some embodiments, the formulation comprises a Tris buffer.
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公开(公告)号：US20200338164A1
公开(公告)日：2020-10-29
申请号：US16764463
申请日：2018-11-16
Applicant: Amgen Inc.
Inventor： Yael WEXLER-COHEN , William J. CALLAHAN , Robert Matthew FESINMEYER , Rahul Rajan KAUSHIK , Sai Chakradhar PADALA
Abstract: Protein formulations and methods of making and using such formulations are provided herein. The formulation can be an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the formulation comprises a VEGFR-Fc fusion protein, such as aflibercept.
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公开(公告)号：US20230025418A1
公开(公告)日：2023-01-26
申请号：US17932255
申请日：2022-09-14
Applicant: Amgen Inc.
Inventor： Yael WEXLER-COHEN , Robert Matthew FESINMEYER , Monica Michelle GOSS , Sekhar KANAPURAM , Rahul Rajan KAUSHIK , Sai Chakradhar PADALA
Abstract: VEGFR-Fc fusion protein formulations and methods of making using such formulations are provided herein. In one embodiment, the formulation is an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the VEGFR-Fc fusion protein is aflibercept.
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公开(公告)号：US20210353713A1
公开(公告)日：2021-11-18
申请号：US17288139
申请日：2019-10-25
Applicant: Amgen Inc.
Inventor： Yael WEXLER-COHEN , Robert Matthew FESINMEYER , Rahul Rajan KAUSHIK
Abstract: Protein formulations and methods of making and using such formulations are provided herein. The formulation can be an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the formulation comprises a VEGFR-Fc fusion protein, such as aflibercept. In some embodiments, the formulation comprises a Tris buffer.
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公开(公告)号：US20200255496A1
公开(公告)日：2020-08-13
申请号：US16647902
申请日：2018-09-17
Applicant: Amgen Inc.
Inventor： Yael WEXLER-COHEN , Robert Matthew FESINMEYER , Monica Michelle GOSS , Sekhar KANAPURAM , Rahul Rajan KAUSHIK , Sai Chakradhar PADALA
Abstract: VEGFR-Fc fusion protein formulations and methods of making using such formulations are provided herein. In one embodiment, the formulation is an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the VEG-FR-Fc fusion protein is aflibercept.
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